Institute of Physics, Khwaja Fareed University of Engineering & Information Technology, Rahim Yar Khan 64200, Pakistan.
Interdisciplinary Research Centre in Biomedical Materials, COMSATS University Islamabad, Lahore, Pakistan.
Nanotechnology. 2024 Sep 26;35(49). doi: 10.1088/1361-6528/ad7b41.
Reliable and cost-effective glucose sensors are in rising demand among diabetes patients. The combination of metals and conducting polymers creates a robust electrocatalyst for glucose oxidation, offering enzyme-free, high stability, and sensitivity with outstanding electrochemical results. Herein, graphene is grown on nickel foam by chemical vapor deposition to make a graphene@nickel foam scaffold (G@NF), on which silver nanoplates-polyaniline (Ag-PANI) 3D architecture is developed by sonication-assisted co-electrodeposition. The resulting binder-free 3D Ag-PANI/G@NF electrode was highly porous, as characterized by x-ray photoelectron spectroscopy, Field emission scanning electron microscope, x-ray diffractometer, FTIR, and Raman spectroscopy. The binder-free 3D Ag-PANI/G@NF electrode exhibits remarkable electrochemical efficiency with a superior electrochemical active surface area. The amperometric analysis provides excellent anti-interference performance, a low limit of deduction (0.1 nM), robust sensitivity (1.7 × 10A mMcm), and a good response time. Moreover, the Ag-PANI/G@NF enzyme-free sensor is utilized to observe glucose levels in human blood serums and exhibits excellent potential to become a reliable clinical glucose sensor.
在糖尿病患者中，可靠且经济高效的葡萄糖传感器的需求日益增长。金属和导电聚合物的组合为葡萄糖氧化提供了一种强大的电催化剂，具有无酶、高稳定性和灵敏度，以及出色的电化学结果。在此，通过化学气相沉积在镍泡沫上生长石墨烯，制得石墨烯@镍泡沫支架（G@NF），通过超声辅助共电沉积在其上开发出银纳米板-聚苯胺（Ag-PANI）3D 结构。所得到的无粘结剂 3D Ag-PANI/G@NF 电极具有高度多孔性，这通过 X 射线光电子能谱、场发射扫描电子显微镜、X 射线衍射仪、FTIR 和拉曼光谱进行了表征。无粘结剂 3D Ag-PANI/G@NF 电极具有出色的电化学效率和优越的电化学活性表面积。安培分析提供了出色的抗干扰性能、低检测限（0.1 nM）、高灵敏度（1.7×10A mMcm）和良好的响应时间。此外，Ag-PANI/G@NF 无酶传感器用于观察人血清中的葡萄糖水平，具有成为可靠临床葡萄糖传感器的巨大潜力。
