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股骨颈骨折全髋关节置换术后10年翻修风险增加。

Increased Risk of 10-Year Revision Following Total Hip Arthroplasty for Femoral Neck Fracture.

作者信息

Zhao Amy Y, Parel Philip M, Agarwal Amil R, Gu Alex, Ranson Rachel A, Das Avilash, Golladay Gregory J, Thakkar Savyasachi C

机构信息

Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Department of Orthopaedic Surgery, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia.

出版信息

J Arthroplasty. 2025 Mar;40(3):688-692. doi: 10.1016/j.arth.2024.09.012. Epub 2024 Sep 14.

Abstract

BACKGROUND

As the incidence of femoral neck fractures (FNFs) increases with the aging population, understanding its impact on surgical outcomes is important to improving implant survival and patient satisfaction. Despite increasing use of total hip arthroplasty (THA) as management for FNF, few studies have examined long-term implant survivability. Thus, this study sought to determine the 10-years cumulative incidence of revision and indications for revision in patients undergoing THA for FNF in comparison to osteoarthritis.

METHODS

Patients who underwent primary THA for FNF or osteoarthritis were identified using a national administrative claims database and propensity-score matched in a 1:2 ratio based on age, gender, the Charlson Comorbidity Index (CCI), smoking, obesity, and diabetes mellitus. Kaplan-Meier and Cox proportional hazards analyses were used to observe the cumulative incidence and risk of all-cause revision, periprosthetic joint infection (PJI), dislocation, mechanical loosening, and periprosthetic fracture (PPF) within 10 years of primary THA. In total, 19,735 patients who underwent THA for FNF and 39,383 patients who underwent THA for osteoarthritis were included.

RESULTS

The 10-years cumulative incidences of all-cause revision (7.1 versus 4.9%), PJI (5.0 versus 3.3%), dislocation (6.8 versus 3.8%), mechanical loosening (3.1 versus 1.9%), and PPF (7.8 versus 4.0%) were significantly higher for those who underwent THA for FNF versus osteoarthritis. Femoral neck fractures were associated with higher risks of revision (hazard ratio [HR]: 1.6), PJI (HR: 1.7), dislocation (HR: 2.0), mechanical loosening (HR: 1.6), and PPF (HR: 2.2) (P < 0.001 for all).

CONCLUSIONS

Despite the advantages of THA, femoral neck fractures remain a major risk factor for long-term complications. Tailored preoperative planning, surgical techniques, and postoperative bone health optimization in these patients may help minimize poor outcomes.

摘要

背景

随着人口老龄化,股骨颈骨折(FNF)的发病率不断上升,了解其对手术结果的影响对于提高植入物存活率和患者满意度至关重要。尽管全髋关节置换术(THA)作为FNF的治疗方法使用越来越多,但很少有研究考察长期植入物的存活率。因此,本研究旨在确定FNF患者与骨关节炎患者相比,接受THA治疗后10年的翻修累积发生率及翻修指征。

方法

利用国家行政索赔数据库确定接受FNF或骨关节炎初次THA的患者,并根据年龄、性别、Charlson合并症指数(CCI)、吸烟、肥胖和糖尿病,按1:2的比例进行倾向评分匹配。采用Kaplan-Meier和Cox比例风险分析观察初次THA后10年内全因翻修、假体周围关节感染(PJI)、脱位、机械性松动和假体周围骨折(PPF)的累积发生率和风险。总共纳入了19735例接受FNF的THA患者和39383例接受骨关节炎的THA患者。

结果

接受FNF的THA患者全因翻修(7.1%对4.9%)、PJI(5.0%对3.3%)、脱位(6.8%对3.8%)、机械性松动(3.1%对1.9%)和PPF(7.8%对4.0%)的10年累积发生率显著高于骨关节炎患者。股骨颈骨折与翻修(风险比[HR]:1.6)、PJI(HR:1.7)、脱位(HR:2.0)、机械性松动(HR:1.6)和PPF(HR:2.2)的较高风险相关(所有P<0.001)。

结论

尽管THA有优势,但股骨颈骨折仍然是长期并发症的主要危险因素。对这些患者进行有针对性的术前规划、手术技术和术后骨健康优化可能有助于减少不良结果。

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