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伴有罕见孤立性脑桥病变的三叉神经痛：一例报告及文献综述

Trigeminal neuralgia with rare solitary pontine lesion: A case report and literature review.

作者信息

Alhijab Ali, Bakhurji Ahmed, Alshammari Rakan, Almatter Abdulla, Bunyan Reem, Bashir Shahid

机构信息

Department of Adult Neurology, Neuroscience Center, King Fahad Specialist Hospital Dammam, Dammam 31444, Saudi Arabia.

Neuroscience Center, King Fahad Specialist Hospital Dammam, Dammam 31444, Saudi Arabia.

出版信息

Radiol Case Rep. 2024 Sep 4;19(11):5519-5522. doi: 10.1016/j.radcr.2024.08.003. eCollection 2024 Nov.

DOI:10.1016/j.radcr.2024.08.003
PMID:39285969
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11403909/
Abstract

Trigeminal neuralgia (TN) associated with brainstem lesions as revealed by Magnetic resonance imaging (MRI), is a rare condition. The MRI often shows a distinctive single pontine in cases of TN (SPL-TN). While the significance of this MRI finding remains unclear, various case reports suggest a potential link to chronic injury in the pontine pathways of the trigeminal nerve. In this report, we present the case of a 42-year-old female who was referred for TN that is refractory to medical treatment with an ipsilateral MRI lesion over the pons who had an excellent response to a trigeminal nerve bock, shedding light on the intriguing interplay between TN and pontine lesions.

摘要

磁共振成像（MRI）显示与脑干病变相关的三叉神经痛（TN）是一种罕见的病症。在三叉神经痛（SPL-TN）病例中，MRI常显示出独特的单个脑桥病变。虽然这一MRI发现的意义尚不清楚，但各种病例报告表明，它可能与三叉神经脑桥通路的慢性损伤有关。在本报告中，我们介绍了一例42岁女性患者，她因药物治疗无效的TN被转诊，其脑桥同侧有MRI病变，对三叉神经阻滞有良好反应，这为TN与脑桥病变之间有趣的相互作用提供了线索。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a29/11403909/4c5f08dc1eb7/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a29/11403909/37f3e7b5aa3a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a29/11403909/bb2be1aef40e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a29/11403909/bbb7a3e95b8f/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a29/11403909/999ebea50498/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a29/11403909/4c5f08dc1eb7/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a29/11403909/37f3e7b5aa3a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a29/11403909/bb2be1aef40e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a29/11403909/bbb7a3e95b8f/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a29/11403909/999ebea50498/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a29/11403909/4c5f08dc1eb7/gr5.jpg

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Trigeminal neuralgia associated with a solitary pontine lesion: clinical and neuroimaging definition of a new syndrome.与单一桥脑病变相关的三叉神经痛：一种新综合征的临床和神经影像学定义。
Pain. 2020 May;161(5):916-925. doi: 10.1097/j.pain.0000000000001777.
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Quant Imaging Med Surg. 2016 Oct;6(5):490-495. doi: 10.21037/qims.2016.01.07.
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