Parra Adrian, Kuker Russ A
Department of Radiology, University of Miami Miller School of Medicine, Miami, USA.
Department of Radiology and Nuclear Medicine, Jackson Memorial Hospital, Miami, USA.
Cureus. 2024 Sep 16;16(9):e69527. doi: 10.7759/cureus.69527. eCollection 2024 Sep.
A diagnosis of calciphylaxis is rare amongst the vulnerable population of patients with end-stage renal disease (ESRD); however, it has poor outcomes when it does present. With ineffective clearance due to reduced kidney function, calcium and phosphorus accumulate and deposit in the intimal layer of blood vessels and other soft tissues throughout the body. It can be proven using biopsy of skin lesions characteristic of the disease or with less invasive methods including X-ray and bone scintigraphy. Calciphylaxis is typically seen in middle-aged patients who have undergone prolonged dialysis treatment and has a devastating prognosis unless the patient can obtain a renal transplant. In this report, we present a case of a 30-year-old female patient with calciphylaxis and highlight the value of bone scintigraphy for diagnosis, while noting the importance of organ transplant for proper treatment.
在终末期肾病（ESRD）这一弱势群体中，钙化防御的诊断较为罕见；然而，一旦出现，其预后很差。由于肾功能减退导致清除无效，钙和磷会在全身血管内膜层和其他软组织中积聚并沉积。可以通过对该病特征性皮肤病变进行活检或采用包括X射线和骨闪烁扫描在内的侵入性较小的方法来证实。钙化防御通常见于接受长期透析治疗的中年患者，除非患者能够接受肾移植，否则预后不佳。在本报告中，我们介绍了一例30岁钙化防御女性患者的病例，强调了骨闪烁扫描在诊断中的价值，同时指出了器官移植在恰当治疗中的重要性。
