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伴有腹膜累及的间变大细胞浆细胞骨髓瘤。

Anaplastic Plasma Cell Myeloma With Peritoneal Involvement.

机构信息

Department of Hematology, Cruces University Hospital, Barakaldo (Bizkaia), Spain.

Department of Pathology, Cruces University Hospital, Barakaldo (Bizkaia), Spain.

出版信息

Diagn Cytopathol. 2024 Dec;52(12):774-778. doi: 10.1002/dc.25403. Epub 2024 Sep 17.

Abstract

Multiple myeloma (MM) is a B-cell neoplasm that rounds 15% of all hematological malignancies. The typical clinical presentation of MM includes hypercalcemia, renal failure, anemia and bone lesion (CRAB). Effusions due to MM may occur due to secondary involvement of other organs and rarely are present at the initial diagnosis. Anaplastic myeloma (AMM) is rare morphological variant of multiple myeloma with predisposition of extramedullary affection. Herein, we describe a case of malignant plasmacytic ascites at disease onset of anaplastic multiple myeloma.

摘要

多发性骨髓瘤(MM)是一种 B 细胞肿瘤,占所有血液系统恶性肿瘤的 15%。MM 的典型临床表现包括高钙血症、肾衰竭、贫血和骨病变(CRAB)。MM 引起的胸腔积液可能由于其他器官的继发累及而发生,在初始诊断时很少出现。间变大细胞骨髓瘤(AMM)是多发性骨髓瘤的罕见形态学变异型,易发生骨髓外累及。本文描述了一例间变大细胞多发性骨髓瘤发病时恶性浆细胞性腹水的病例。

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