Clinical Institute of Radiology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Radiol Oncol. 2024 Sep 15;58(3):397-405. doi: 10.2478/raon-2024-0037. eCollection 2024 Sep 1.
This study aimed to evaluate the safety and efficacy of emergency and prophylactic uterine artery embolization (UAE) in our clinical practice, including technical success, clinical success, and associated complications.
In this retrospective study, we analyzed 64 women who underwent emergency ( =18) and prophylactic ( = 46) UAE. Indications for emergency UAE included postpartum hemorrhage or severe hemorrhage during pregnancy termination, while prophylactic UAE was performed prior to surgical removal of retained products of conception (RPOC), delivery with abnormal placental implantation, or pregnancy termination (cervical pregnancy or fetal anomalies accompanied by abnormal placental implantation). Technical success of UAE was defined as complete exclusion of the vascular lesion and contrast stasis on the final angiogram, while clinical success was defined as cessation of bleeding after UAE Termination without a hysterectomy.
The overall clinical success of UAE in our study was 97% (62/64). All embolization procedures were technically and clinically successful in the prophylactic group without life-threatening hemorrhages or hysterectomies (100% success rate, 46/46). However, while 100% technical success was similarly attained in the emergency group, bleeding was successfully controlled in 89% of cases (16/18). In two patients with significant blood loss (over 2000 mL), embolization failed to achieve hemostasis, resulting in persistent bleeding and subsequent hysterectomy.
UAE is a safe and effective procedure for managing primary postpartum hemorrhage or severe hemorrhage during pregnancy termination and for decreasing the risk of severe hemorrhage during surgical removal of RPOC, delivery with abnormal placental implantation, or pregnancy.
本研究旨在评估紧急和预防性子宫动脉栓塞术(UAE)在我们的临床实践中的安全性和有效性,包括技术成功、临床成功和相关并发症。
在这项回顾性研究中,我们分析了 64 名接受紧急(=18)和预防性(=46)UAE 的女性。紧急 UAE 的适应证包括产后出血或妊娠终止时严重出血,而预防性 UAE 则在手术切除残留妊娠产物(RPOC)、异常胎盘植入分娩或妊娠终止(宫颈妊娠或胎儿异常伴异常胎盘植入)前进行。UAE 的技术成功定义为最终血管造影显示血管病变完全排除且对比剂停滞,而临床成功定义为 UAE 终止后无子宫切除的出血停止。
我们研究中 UAE 的总体临床成功率为 97%(62/64)。预防性组的所有栓塞术均在技术上和临床上均成功,无危及生命的出血或子宫切除术(成功率 100%,46/46)。然而,在紧急组中,虽然同样达到了 100%的技术成功率,但仅 89%的病例(16/18)成功控制了出血。在两名大出血患者(超过 2000 毫升)中,栓塞未能止血,导致持续出血和随后的子宫切除术。
UAE 是一种安全有效的治疗产后出血或妊娠终止时严重出血的方法,可降低手术切除 RPOC、异常胎盘植入分娩或妊娠时严重出血的风险。