Department of Dentistry, Ng Teng Fong General Hospital and Faculty of Dentistry, National University Health System, Singapore, Singapore.
National Dental Centre Singapore and Duke-NUS Medical School, Singapore Health Services, National Dental Research Institute Singapore, Singapore, Singapore.
J Oral Rehabil. 2024 Dec;51(12):2566-2576. doi: 10.1111/joor.13857. Epub 2024 Sep 17.
The relationship of somatisation with facial pain duration/intensity, pain-related interference/disability and psychological distress was investigated in East Asian temporomandibular disorder (TMD) patients. Correlations between somatisation, facial pain and psychological characteristics were also explored alongside the demographic/physical factors associated with moderate-to-severe depression and anxiety.
Anonymised data were acquired from records of consecutive 'first-time' patients seeking TMD care at a tertiary oral medicine clinic. Axis I physical TMD diagnoses were established utilising the diagnostic criteria for TMDs (DC/TMD) protocol and patients with TMD pain were stratified into those with pain-related (PT) and combined (CT) conditions. Axis II measures administered encompassed the Patient Health Questionnaire-15 (PHQ-15), Graded Chronic Pain Scale (GCPS), Patient Health Questionnaire-9 (PHQ-9) and General Anxiety Disorder Scale-7 (GAD-7). Individuals with PT and CT were further categorised into those without (Pain - Som/Comb - Som) and with somatisation (Pain + Som/Comb + Som). Statistical evaluations were performed with nonparametric and logistic regression analyses (α = 0.05).
The final sample comprised 473 patients (mean age 36.2 ± 14.8 years; 68.9% women), of which 52.0% had concomitant somatisation. Significant differences in pain duration (Comb + Som > Pain - Som), pain-related interference/disability (Comb + Som > Comb - Som) and depression/anxiety (Pain + Som, Comb + Som > Pain - Som, Comb - Som) were discerned. Depression/anxiety was moderately correlated with somatisation (r = 0.64/0.52) but not facial pain characteristics. Multivariate modelling revealed that somatisation was significantly associated with the prospects of moderate-to-severe depression (OR 1.35) and anxiety (OR 1.24).
Somatisation exhibited a strong association with psychological distress when contrasted with facial pain in East Asian TMD patients.
本研究旨在探讨躯体化与东亚颞下颌关节紊乱病(TMD)患者面部疼痛持续时间/强度、疼痛相关干扰/残疾和心理困扰之间的关系。同时,还探讨了躯体化与面部疼痛以及心理特征之间的相关性,以及与中重度抑郁和焦虑相关的人口统计学/身体因素。
从一家三级口腔医学诊所接受 TMD 治疗的“首次”连续就诊患者的记录中获取匿名数据。利用 TMD 诊断标准(DC/TMD 方案)确定 I 轴躯体 TMD 诊断,将 TMD 疼痛患者分为与疼痛相关(PT)和混合(CT)两种情况。实施的 II 轴测量包括患者健康问卷-15 项(PHQ-15)、慢性疼痛分级量表(GCPS)、患者健康问卷-9 项(PHQ-9)和广泛性焦虑障碍量表-7 项(GAD-7)。将 PT 和 CT 患者进一步分为无躯体化(疼痛-躯体/混合-躯体)和躯体化(疼痛+躯体/混合+躯体)患者。使用非参数和逻辑回归分析进行统计评估(α=0.05)。
最终样本包括 473 名患者(平均年龄 36.2±14.8 岁;68.9%为女性),其中 52.0%伴有躯体化。在疼痛持续时间(混合+躯体>疼痛-躯体)、疼痛相关干扰/残疾(混合+躯体>混合-躯体)和抑郁/焦虑(疼痛+躯体,混合+躯体>疼痛-躯体,混合-躯体)方面存在显著差异。抑郁/焦虑与躯体化中度相关(r=0.64/0.52),但与面部疼痛特征无关。多变量建模显示,躯体化与中重度抑郁(OR 1.35)和焦虑(OR 1.24)的发生显著相关。
与东亚 TMD 患者的面部疼痛相比,躯体化与心理困扰具有更强的相关性。