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脑肿瘤手术中的多模态结构和功能监测:IONM 和 IOUS 的作用。

Multimodality Structural and Functional Monitoring in Brain Tumor Surgery: The Role of IONM and IOUS.

机构信息

Brain Tumor and Translational Neuroscience Centre, Department of Neurosurgery, University of Pretoria, Steve Biko Academic Hospital, Pretoria, South Africa.

Acoustic Neuro-Imaging and Therapy Lab (ANTY-Lab), Department of Neurosurgery, Fondazione IRCCS Istituto C. Besta, Milan, Italy.

出版信息

Adv Tech Stand Neurosurg. 2024;53:1-12. doi: 10.1007/978-3-031-67077-0_1.

DOI:10.1007/978-3-031-67077-0_1
PMID:39287799
Abstract

Brain tumor surgery represents the pinnacle of technical and technological advances in the neurosurgery. The goal remains optimized extent of resection with preservation of neurological function. The benefit of a multimodal structural and functional intra-operative monitoring approach is to improve the ability of the surgeon to achieve the goal of optimized surgical resection. Despite significant technological advances, challenges in defining tumor and functional neural tissue interface remain a significant barrier. The opportunity to address this challenge, however, presents us with an exciting path ahead.

摘要

脑肿瘤手术代表了神经外科学在技术和技术进步方面的巅峰。目标仍然是在保留神经功能的情况下最大限度地切除肿瘤。多模态结构和功能术中监测方法的益处在于提高外科医生实现最佳手术切除目标的能力。尽管取得了重大技术进步,但在定义肿瘤和功能神经组织界面方面仍然存在重大挑战。然而,有机会解决这一挑战,为我们提供了一个令人兴奋的前进道路。

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本文引用的文献

1
Intraoperative Imaging and Optical Visualization Techniques for Brain Tumor Resection: A Narrative Review.脑肿瘤切除术中的成像与光学可视化技术:一项叙述性综述
Cancers (Basel). 2023 Oct 9;15(19):4890. doi: 10.3390/cancers15194890.
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Intraoperative MRI-Guided Resection Is Not Superior to 5-Aminolevulinic Acid Guidance in Newly Diagnosed Glioblastoma: A Prospective Controlled Multicenter Clinical Trial.术中磁共振引导切除并不优于 5-氨基酮戊酸引导在新诊断的胶质母细胞瘤:一项前瞻性对照多中心临床试验。
J Clin Oncol. 2023 Dec 20;41(36):5512-5523. doi: 10.1200/JCO.22.01862. Epub 2023 Jun 19.
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Turning on the light for brain tumor surgery: A 5-aminolevulinic acid story.
脑肿瘤手术中的“明灯”:5-氨基酮戊酸的故事。
Neuro Oncol. 2022 Nov 2;24(Suppl 6):S52-S61. doi: 10.1093/neuonc/noac191.
4
Intraoperative ultrasound in brain tumor surgery: A review and implementation guide.术中超声在脑肿瘤手术中的应用:综述与实施指南。
Neurosurg Rev. 2022 Aug;45(4):2503-2515. doi: 10.1007/s10143-022-01778-4. Epub 2022 Mar 30.
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5-Aminolevulinic acid for enhanced surgical visualization of high-grade gliomas: a prospective, multicenter study.5-氨基酮戊酸用于增强高级别胶质瘤手术可视化:一项前瞻性多中心研究。
J Neurosurg. 2021 Oct 8;136(6):1525-1534. doi: 10.3171/2021.5.JNS21310. Print 2022 Jun 1.
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Intraoperative Neuromonitoring During Resection of Gliomas Involving Eloquent Areas.涉及明确功能区的胶质瘤切除术中的术中神经监测
Front Neurol. 2021 Jun 23;12:658680. doi: 10.3389/fneur.2021.658680. eCollection 2021.
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Intraoperative B-Mode Ultrasound Guided Surgery and the Extent of Glioblastoma Resection: A Randomized Controlled Trial.术中B超引导手术与胶质母细胞瘤切除范围:一项随机对照试验
Front Oncol. 2021 May 19;11:649797. doi: 10.3389/fonc.2021.649797. eCollection 2021.
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5-ALA Fluorescence Is a Powerful Prognostic Marker during Surgery of Low-Grade Gliomas (WHO Grade II)-Experience at Two Specialized Centers.5-氨基乙酰丙酸荧光是低级别胶质瘤(世界卫生组织二级)手术期间强有力的预后标志物——两个专业中心的经验。
Cancers (Basel). 2021 May 21;13(11):2540. doi: 10.3390/cancers13112540.
9
Challenges and Opportunities of Intraoperative 3D Ultrasound With Neuronavigation in Relation to Intraoperative MRI.术中三维超声与神经导航结合相对于术中磁共振成像的挑战与机遇
Front Oncol. 2021 May 3;11:656519. doi: 10.3389/fonc.2021.656519. eCollection 2021.
10
Case Report: Multimodal Functional and Structural Evaluation Combining Pre-operative nTMS Mapping and Neuroimaging With Intraoperative CT-Scan and Brain Shift Correction for Brain Tumor Surgical Resection.病例报告:术前nTMS映射与神经影像学相结合,术中CT扫描及脑移位校正用于脑肿瘤手术切除的多模态功能和结构评估
Front Hum Neurosci. 2021 Feb 25;15:646268. doi: 10.3389/fnhum.2021.646268. eCollection 2021.