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临床观点、资格和减重/代谢手术的成功标准。

Clinical Perspectives, Eligibility, and Success Criteria for Bariatric/Metabolic Surgery.

机构信息

Department of Endocrinology & Nutrition, Clínica Universidad de Navarra, University of Navarra, IdiSNA, Pamplona, Spain.

CIBEROBN, Instituto de Salud Carlos III, Pamplona, Spain.

出版信息

Adv Exp Med Biol. 2024;1460:677-695. doi: 10.1007/978-3-031-63657-8_23.

Abstract

Obesity is a worldwide chronic, complex, and progressive disease that poses a challenge for physicians to pursue optimal therapeutic decision making. This chapter focuses on the definition of obesity, based on excessive fat accumulation, and thus underscores the importance of body composition, and the clinical tools used to diagnose it in the context of excess weight, metabolic alteration, and obesity-associated comorbidity development. Additionally, it addresses the indications for surgery that are currently applicable and the description of the different types of patients who could benefit the most from the surgical management of excessive body fat and its associated metabolic derangements and quality of life improvement. Furthermore, it also highlights plausible underlying mechanisms of action for the beneficial effects following bariatric/metabolic surgery.

摘要

肥胖是一种全球性的慢性、复杂和进行性疾病,给医生追求最佳治疗决策带来了挑战。本章重点介绍肥胖的定义,基于过多的脂肪积累,因此强调了身体成分的重要性,以及在超重、代谢改变和肥胖相关并发症发展的背景下用于诊断肥胖的临床工具。此外,还讨论了目前适用的手术适应证,以及描述了不同类型的患者最有可能受益于手术治疗过多的体脂及其相关代谢紊乱和生活质量改善。此外,它还强调了减重/代谢手术后有益效果的可能潜在作用机制。

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