From Data Mining to Discovery: SNHG11 as a Therapeutic Target in Pulmonary Hypertension.
作者信息
Grobs Yann, Potus Francois
机构信息
Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec Québec City, Québec, Canada.
出版信息
Am J Respir Cell Mol Biol. 2025 Mar;72(3):227-228. doi: 10.1165/rcmb.2024-0415ED.
Abstract
摘要
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本文引用的文献
1
Identification of SNHG11 as a Therapeutic Target in Pulmonary Hypertension.
Am J Respir Cell Mol Biol. 2025 Mar;72(3):244-257. doi: 10.1165/rcmb.2023-0428OC.
2
The lncRNA Snhg11, a new candidate contributing to neurogenesis, plasticity, and memory deficits in Down syndrome.长链非编码 RNA Snhg11 是促进唐氏综合征神经发生、可塑性和记忆缺陷的新候选基因。
Mol Psychiatry. 2024 Jul;29(7):2117-2134. doi: 10.1038/s41380-024-02440-9. Epub 2024 Feb 27.
3
Long noncoding RNA SNHG1 alleviates high glucose-induced vascular smooth muscle cells calcification/senescence by post-transcriptionally regulating Bhlhe40 and autophagy via Atg10.长链非编码 RNA SNHG1 通过转录后调控 Bhlhe40 和自噬来减轻高糖诱导的血管平滑肌细胞钙化/衰老，其作用途径为 Atg10。
J Physiol Biochem. 2023 Feb;79(1):83-105. doi: 10.1007/s13105-022-00924-2. Epub 2022 Oct 4.
4
Circular RNAs in pulmonary hypertension: Emerging biological concepts and potential mechanism.环状 RNA 在肺动脉高压中的作用：新兴的生物学概念和潜在机制。
Animal Model Exp Med. 2022 Feb;5(1):38-47. doi: 10.1002/ame2.12208. Epub 2022 Jan 27.
5
LncRNA SNHG11 aggravates cell proliferation and migration in triple-negative breast cancer via sponging miR-2355-5p and targeting CBX5.长链非编码RNA SNHG11通过吸附miR-2355-5p并靶向CBX5促进三阴性乳腺癌细胞的增殖和迁移。
Exp Ther Med. 2021 Aug;22(2):892. doi: 10.3892/etm.2021.10324. Epub 2021 Jun 18.
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Dysregulation of lncRNA SNHG1/miR-145 axis affects the biological function of human carotid artery smooth muscle cells as a mechanism of carotid artery restenosis.lncRNA SNHG1/miR-145轴的失调影响人颈动脉平滑肌细胞的生物学功能，作为颈动脉再狭窄的一种机制。
Exp Ther Med. 2021 May;21(5):423. doi: 10.3892/etm.2021.9867. Epub 2021 Feb 25.
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lncRNA SNHG11 Promotes Gastric Cancer Progression by Activating the Wnt/β-Catenin Pathway and Oncogenic Autophagy.lncRNA SNHG11 通过激活 Wnt/β-连环蛋白通路和致癌性自噬促进胃癌进展。
Mol Ther. 2021 Mar 3;29(3):1258-1278. doi: 10.1016/j.ymthe.2020.10.011. Epub 2020 Oct 15.
8
LncRNA SNHG11 facilitates tumor metastasis by interacting with and stabilizing HIF-1α.长链非编码 RNA SNHG11 通过与 HIF-1α 相互作用并使其稳定来促进肿瘤转移。
Oncogene. 2020 Nov;39(46):7005-7018. doi: 10.1038/s41388-020-01512-8. Epub 2020 Oct 15.
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