Bab I, Lustmann J, Azaz B, Gazit D, Garfunkel A
J Oral Pathol. 1985 Aug;14(7):573-80. doi: 10.1111/j.1600-0714.1985.tb00531.x.
Tissue samples obtained from human gingiva with soft tissue calcification were processed for light and transmission electron microscopy. The stroma in these specimens revealed numerous foci of calcification in a matrix that consisted of closely packed branching microfibrils, 12 nm in diameter and a maximum of 2.5 micron in length. Calcospherites, 0.25-1.11 micron in diameter, were present within the matrix. They were constructed of needle-like units shown by high resolution electron microscopy and energy dispersive X-ray microanalysis to be apatite. Larger calcified masses were composed of calcospherites which were fused together. Matrix vesicles or other forms of membraneous material could not be found. The relationship between the mineral and non-collagenous microfibrils may suggest a role for the latter in the onset of calcification in this ectopic site.
从患有软组织钙化的人牙龈获取组织样本，进行光镜和透射电镜检查。这些标本中的基质显示出大量钙化灶，其基质由紧密排列的分支微纤维组成，直径为12纳米，长度最大为2.5微米。基质中存在直径为0.25 - 1.11微米的钙球。高分辨率电子显微镜和能量色散X射线微分析显示，它们由针状单元构成，为磷灰石。较大的钙化团块由融合在一起的钙球组成。未发现基质小泡或其他形式的膜性物质。矿物质与非胶原微纤维之间的关系可能表明后者在这个异位部位钙化的起始过程中发挥作用。
