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巴西亚马逊贫困城市社区成年人中梅毒螺旋体感染的流行情况及相关决定因素。

Prevalence and determinants associated with T. pallidum infection in adults from poor urban communities, Brazilian Amazon.

机构信息

Universidade Federal do Pará, Programa de Pós-Graduação em Enfermagem, Belém 66075-110, Brazil.

Universidade Federal do Pará, Programa de Pós-Graduação em Enfermagem, Belém 66075-110, Brazil.

出版信息

J Infect Public Health. 2024 Oct;17(10):102543. doi: 10.1016/j.jiph.2024.102543. Epub 2024 Sep 12.

DOI:10.1016/j.jiph.2024.102543
PMID:39288680
Abstract

BACKGROUND

In Brazil, despite the increase in coverage and access to rapid testing for syphilis in primary health care, no reduction in cases of syphilis and congenital syphilis was observed. Poor and low-educated populations are disproportionately affected by infection caused by T. pallidum. This study aims to estimate the prevalence of syphilis and associated factors among people aged 18 to 49 years old in the city of Belém, brazilian amazon.

METHODS

Observational, cross-sectional study carried out in a sanitary administrative district of a capital of the Brazilian Amazon, Belém, state of Pará, Brazil. Data collection was conducted from August 2021 to February 2022. The participantes consisted of residents of the Montese, Guamá and Condor neighborhoods. People aged 18 to 49 years were included. This variable was treated as dichotomous (reagent and non-reagent). The selected response event was 'reagent result'. The independent variables were the social factors and access to health services. To identify associated factors with the presence of markers of the bacteria studied, multiple logistic rules were performed.

RESULTS

178 people participated in the study; the median age was 35.0 years. The prevalence of IgG and/or IgM antibodies against T. pallidum was 7 % (13). In the final regression model, it was observed that participants who had sexual intercourse after using alcohol and drugs and those who did not know about the prevention of sexually transmitted infections were five times more likely to have tested positive for T. pallidum.

CONCLUSIONS

Aspects of individual vulnerability and access to health services must be managed to reduce the exposure of poor urban populations to T. pallidum.

摘要

背景

在巴西,尽管基层医疗保健中梅毒快速检测的覆盖率和可及性有所增加,但梅毒和先天性梅毒的病例并未减少。贫穷和受教育程度低的人群不成比例地受到苍白密螺旋体感染的影响。本研究旨在估计巴西亚马逊州贝伦市 18 至 49 岁人群中梅毒的流行率及相关因素。

方法

这是一项在巴西亚马逊州首府贝伦市一个卫生行政区进行的观察性、横断面研究。数据收集于 2021 年 8 月至 2022 年 2 月进行。参与者包括 Montese、Guamá 和 Condor 社区的居民。纳入年龄在 18 至 49 岁的人群。该变量被视为二分类(试剂和非试剂)。选择的反应事件是“试剂结果”。自变量是社会因素和获得卫生服务的情况。为了确定与研究细菌存在相关的因素,进行了多项逻辑回归分析。

结果

共有 178 人参加了研究,中位数年龄为 35.0 岁。针对苍白密螺旋体的 IgG 和/或 IgM 抗体的阳性率为 7%(13 例)。在最终的回归模型中,观察到在发生性行为后使用酒精和毒品且不知道预防性传播感染的参与者,其梅毒检测呈阳性的可能性是其他参与者的五倍。

结论

必须管理个体脆弱性和获得卫生服务的方面,以减少贫困城市人口接触苍白密螺旋体的机会。

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