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[不可切除胰腺癌的术中放疗]

[Intraoperative radiotherapy of unresectable pancreatic carcinoma].

作者信息

Kita M, Okawa T, Goto M, Watanabe N, Sekiguchi K, Ikeda M, Nakamura K, Hanyu F

出版信息

Gan No Rinsho. 1985 Jun;31(7):833-8.

PMID:3928943
Abstract

Twenty-eight cases of unresectable pancreatic carcinoma were treated with intraoperative radiotherapy (IOR) with or without postoperative radiotherapy (POR) from 1975 to 1982 at Tokyo Women's Medical College. The results were as follows. IOR was effective for pain relief, and the response rate was 93%. Twenty-five Gy of IOR, considering sequential POR, was a reasonable dose in about an 8 X 8 cm to 10 X 10 cm radiation field. Precise staging and marking of the tumor edge at operation were important for the treatment planning after IOR. Radiotherapy should be considered in the multimodal treatment of pancreatic carcinoma.

摘要

1975年至1982年期间,东京女子医科大学对28例无法切除的胰腺癌患者进行了术中放疗(IOR),部分患者还接受了术后放疗(POR)。结果如下:术中放疗对缓解疼痛有效,有效率为93%。考虑到后续的术后放疗,在约8×8厘米至10×10厘米的放射野中,25戈瑞的术中放疗剂量是合理的。手术时对肿瘤进行精确分期和标记肿瘤边缘对于术中放疗后的治疗计划很重要。在胰腺癌的多模式治疗中应考虑放疗。

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