Inhibitory effects against zoonotic bacteria by ointment and effects to dog wound.

A topical antimicrobial ointment was developed from the fruit extract of and was evaluated for its antibacterial and wound-healing effects and acute toxicity in animal models. fruit and seed extracts exhibited antibacterial activities against clinically isolated bacteria and showed antioxidant activities. To develop a topical antimicrobial ointment from the fruit extract of and evaluate for its antibacterial and wound-healing effects. fruit extract ointment was prepared and qualitatively controlled. Acute toxicity of the extract was evaluated in the animal model. Antibacterial effects and healing effects of the ointment to the dog wound were investigated. The results are expressed as mean ± standard deviation. The ointment exhibited antibacterial effects. A single daily application of the ointment to a dog's wound exhibited a wound-healing effect with complete epithelialization within 7 days while the wound was completely healed with the removal of the scabs, the size was decreased to 14% of the original size within 12 days. The ointment was found no acute toxicity in the animal model. ointment promoted antibacterial activity and wound-healing effect in dogs with no acute toxicity.