Callaghan Amy, El-Hakim Hamdy, Isaac Andre
Division of Pediatric Surgery, Department of Surgery, Stollery Children's Hospital, University of Alberta, Edmonton, AB, Canada.
Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Alberta, Edmonton, AB, Canada.
Front Pediatr. 2024 Sep 3;12:1460342. doi: 10.3389/fped.2024.1460342. eCollection 2024.
Unilateral vocal cord paralysis (UVCP) is a growing area of research in pediatrics as it spans across many specialties including otolaryngology, cardiology, general surgery, respirology, and speech language pathology. Iatrogenic injury is the most common cause of UVCP, however there is a wide range of data reporting the prevalence, symptom burden, and best treatment practice for this condition. The literature included systematic reviews and meta-analyses, retrospective studies and limited prospective studies. Overall, the literature lacked consistency in the diagnosis, treatment, and long-term outcomes of patients with UVCP. Many articles conflated bilateral vocal cord paralysis (BVCP) with UVCP and had limited data on the natural history of the condition. There was no consensus on objective and subjective measurements to evaluate the condition or best indications for requiring surgical intervention. Thyroplasty, injection medialization (IM) and recurrent laryngeal nerve reinnervation (RLNR) were the reported surgical interventions used to treat UVCP, however there was limited data on short and long-term surgical outcomes in children. More research is needed to determine the true prevalence, natural history, indications for surgical intervention and long-term outcomes for pediatric patients with this condition.
单侧声带麻痹（UVCP）是儿科学领域中一个不断发展的研究方向，因为它涉及许多专业领域，包括耳鼻喉科、心脏病学、普通外科、呼吸病学和言语语言病理学。医源性损伤是UVCP最常见的病因，然而，关于这种疾病的患病率、症状负担和最佳治疗方法，有大量不同的数据报道。文献包括系统评价和荟萃分析、回顾性研究以及有限的前瞻性研究。总体而言，文献在UVCP患者的诊断、治疗和长期预后方面缺乏一致性。许多文章将双侧声带麻痹（BVCP）与UVCP混为一谈，且关于该疾病自然史的数据有限。在评估病情的客观和主观测量方法或手术干预的最佳指征方面，尚未达成共识。据报道，用于治疗UVCP的手术干预措施包括甲状成形术、注射式声带内移术（IM）和喉返神经再支配术（RLNR），然而，关于儿童手术短期和长期预后的数据有限。需要更多的研究来确定患有这种疾病的儿科患者的真实患病率、自然史、手术干预指征和长期预后。
