Salehi Reza, Alizadeh-Otaghvar Hamidreza, Farhadi Bahar, Najafi Masoomeh, Torabi Hossein, Hojjati Hamid, Garrosi Lida, Mirzaei Samira, Farzan Ramyar, Kazemi-Sufi Siamak
Department of Anesthesiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Department of Plastic & Reconstructive Surgery, School of Medicine, Trauma and Injury Research Center, Shahid Motahari Burns Hospital, Iran University of Medical Sciences, Tehran, Iran.
Arch Acad Emerg Med. 2024 Jun 5;12(1):e54. doi: 10.22037/aaem.v12i1.2308. eCollection 2024.
One of the worrisome complications of hip arthroplasty is surgical site infection (SSI). This study aimed to investigate the prevalence of SSI after hip arthroplasty.
A comprehensive and systematic exploration was conducted across various international electronic databases, including Scopus, PubMed, and Web of Science, alongside Persian electronic databases such as Iranmedex and the Scientific Information Database (SID). This search strategy entailed the utilization of Medical Subject Headings-derived keywords such as "Prevalence," "Surgical wound infection," "Surgical site infection," and "Arthroplasty," spanning from the earliest records up to January 1, 2024. Each study's weight was assigned based on its inverse variance. A forest plot visualization was used to assess the studies' heterogeneity. Data on sample size and SSI frequency were compiled for each study to calculate the overall effect size.
The study encompassed a cumulative participant cohort of 1,070,638 hip arthroplasty procedures drawn from seventeen selected studies. Notably, the female gender constituted 59.10% of the overall participant demographic. The aggregate SSI among patients undergoing hip arthroplasty was estimated to be 1.9% (95% CI: 1.3% to 2.8%; I=99.688%; P<0.001). The results of the meta-regression analysis unveiled a statistically significant correlation between the prevalence of SSIs after hip arthroplasty and the year of publication (Coefficient=-0.0020; 95% CI: -0.0021 to -0.0018; Z=-19.39, P<0.001).
The study findings indicated a prevalence rate of 1.9% for SSI following hip arthroplasty. This prevalence underscores the importance of vigilance in infection prevention and management strategies within orthopedic surgery. However, it is essential to acknowledge the variability in SSI prevalence observed across diverse studies, which can be attributed to multifaceted factors, notably variances in patient populations and associated risk factors.
髋关节置换术令人担忧的并发症之一是手术部位感染（SSI）。本研究旨在调查髋关节置换术后SSI的发生率。
对包括Scopus、PubMed和Web of Science在内的各种国际电子数据库以及伊朗医学索引（Iranmedex）和科学信息数据库（SID）等波斯电子数据库进行了全面系统的检索。该检索策略使用了从医学主题词衍生而来的关键词，如“发生率”“手术伤口感染”“手术部位感染”和“关节成形术”，检索时间跨度从最早记录至2024年1月1日。根据各研究的逆方差分配权重。采用森林图可视化评估研究的异质性。汇总各研究的样本量和SSI频率数据以计算总体效应量。
该研究纳入了来自17项选定研究的总计1,070,638例髋关节置换手术参与者队列。值得注意的是，女性占总体参与者人口统计学的59.10%。髋关节置换术患者的总体SSI估计为1.9%（95%置信区间：1.3%至2.8%；I² = 99.688%；P < 0.001）。元回归分析结果显示，髋关节置换术后SSI的发生率与发表年份之间存在统计学显著相关性（系数 = -0.0020；95%置信区间：-0.0021至-0.0018；Z = -19.39，P < 0.001）。
研究结果表明髋关节置换术后SSI的发生率为1.9%。这一发生率凸显了在骨科手术中预防和管理感染策略时保持警惕的重要性。然而，必须认识到不同研究中观察到的SSI发生率存在差异，这可归因于多方面因素，尤其是患者群体和相关风险因素的差异。
