The Soft-Strain Effect Enabled High-Performance Flexible Pressure Sensor and Its Application in Monitoring Pulse Waves.

Flexible and wearable pressure sensors attached to human skin are effective and convenient in accurate and real-time tracking of various physiological signals for disease diagnosis and health assessment. Conventional flexible pressure sensors are constructed using compressible dielectric or conductive layers, which are electrically sensitive to external mechanical stimulation. However, saturated deformation under large compression significantly restrains the detection range and sensitivity of such sensors. Here, we report a novel type of flexible pressure sensor to overcome the compression saturation of the sensing layer by soft-strain effect, enabling an ultra-high sensitivity of ~636 kPa and a wide detection range from 0.1 kPa to 56 kPa. In addition, the cyclic loading-unloading test reveals the excellent stability of the sensor, which maintains its signal detection after 10,000 cycles of 10 kPa compression. The sensor is capable of monitoring arterial pulse waves from both deep tissue and distal parts, such as digital arteries and dorsal pedal arteries, which can be used for blood pressure estimation by pulse transit time at the same artery branch.