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免疫功能正常婴儿发生的危及生命的眼眶周围铜绿假单胞菌坏死性筋膜炎。

Life-threatening periocular pseudomonal necrotizing fasciitis in an immunocompetent infant.

作者信息

Abrams Leora, Pirakitikulr Nathan, Rootman Daniel B

机构信息

Kirk Kerkorian School of Medicine at UNLV, United States.

Division of Orbital and Ophthalmic Plastic Surgery, Department of Ophthalmology, University of California Los Angeles, United States.

出版信息

Am J Ophthalmol Case Rep. 2024 Sep 2;36:102149. doi: 10.1016/j.ajoc.2024.102149. eCollection 2024 Dec.

Abstract

PURPOSE

Necrotizing fasciitis, a severe soft tissue bacterial infection, is uncommon in the periocular region due to its rich blood supply. This report highlights a rare case in an immunocompetent infant.

OBSERVATIONS

A 10-month-old immunocompetent female exhibited fever, irritability, and right eyelid swelling post-fall. Despite initial treatment with cephalexin for presumed cellulitis, her condition rapidly deteriorated, suggesting necrotizing fasciitis. She stabilized after receiving broad-spectrum intravenous antibiotics and aggressive surgical debridement but later required orbital exenteration due to extensive tissue necrosis.

CONCLUSIONS AND IMPORTANCE

Periocular necrotizing fasciitis is exceedingly rare, particularly in immunocompetent individuals. Prompt diagnosis and treatment are critical to mitigate morbidity and mortality.

摘要

目的

坏死性筋膜炎是一种严重的软组织细菌感染,由于眼周区域血供丰富,在该区域并不常见。本报告重点介绍了一例免疫功能正常婴儿的罕见病例。

观察结果

一名10个月大免疫功能正常的女性在跌倒后出现发热、烦躁和右眼睑肿胀。尽管最初因疑似蜂窝织炎使用头孢氨苄进行治疗,但她的病情迅速恶化,提示为坏死性筋膜炎。在接受广谱静脉抗生素治疗和积极的手术清创后病情稳定,但后来由于广泛的组织坏死而需要进行眼眶内容物剜除术。

结论与重要性

眼周坏死性筋膜炎极为罕见,尤其是在免疫功能正常的个体中。及时诊断和治疗对于降低发病率和死亡率至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c54/11405622/760bfb918717/gr1.jpg

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