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迷幻科学的当前趋势:将修饰的麦角酸衍生物和裸盖菇素整合到现代医学中。

Current Trends in Psychedelic Science: Integrating Modified Lysergic Acid Derivatives and Psilocybin in Modern Medicine.

作者信息

Kargbo Robert B

机构信息

Usona Institute, Fitchburg, Wisconsin 53711-5300, United States.

出版信息

ACS Med Chem Lett. 2024 Aug 21;15(9):1443-1445. doi: 10.1021/acsmedchemlett.4c00414. eCollection 2024 Sep 12.

Abstract

This article explores groundbreaking advancements in psychedelic research, highlighting the development of novel lysergic acid derivatives with modified LSD-like actions and innovative dosing methods based on ABCF1 gene expression for psilocybin. It also examines new strategies for treating binge eating disorder using psychedelics and techniques for neuroenhancement to enhance emotional responses. These developments offer fresh insights into the therapeutic potential of psychedelics, underscoring their significance in personalized medicine and mental health treatment. The article delves into the implications of these novel approaches, signaling a transformative phase in the application of psychedelics in clinical settings.

摘要

本文探讨了迷幻药研究中的突破性进展,重点介绍了具有类似LSD修饰作用的新型麦角酸衍生物的开发,以及基于ABCF1基因表达的裸盖菇素创新给药方法。它还研究了使用迷幻药治疗暴饮暴食症的新策略以及增强情绪反应的神经增强技术。这些进展为迷幻药的治疗潜力提供了新的见解,强调了它们在个性化医疗和心理健康治疗中的重要性。文章深入探讨了这些新方法的影响,标志着迷幻药在临床应用中进入了一个变革阶段。

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本文引用的文献

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Expectancy Effects in Psychedelic Trials.迷幻药试验中的期待效应。
Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 May;9(5):512-521. doi: 10.1016/j.bpsc.2024.02.004. Epub 2024 Feb 20.
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The Psychedelic Future of Post-Traumatic Stress Disorder Treatment.创伤后应激障碍治疗的迷幻未来。
Curr Neuropharmacol. 2024;22(4):636-735. doi: 10.2174/1570159X22666231027111147.
6
Psychedelia: The interplay of music and psychedelics.迷幻:音乐与迷幻剂的相互作用。
Ann N Y Acad Sci. 2024 Jan;1531(1):12-28. doi: 10.1111/nyas.15082. Epub 2023 Nov 20.

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