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原发性中枢神经系统淋巴瘤的[18F]FDG PET/CT表现谱——图文综述

Spectrum of [18F]FDG PET/CT Findings in Primary Central Nervous System Lymphoma - A Pictorial Essay.

作者信息

Nithya V, Valaiyapathy N C, Hemalatha Dhamarcherla S, Ramya Priya Rallapeta, Bhargavi D, Kalawat Tekchand

机构信息

Department of Nuclear Medicine, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.

Department of Medical Oncology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.

出版信息

Indian J Nucl Med. 2024 May-Jun;39(3):191-197. doi: 10.4103/ijnm.ijnm_21_24. Epub 2024 Aug 17.

DOI:10.4103/ijnm.ijnm_21_24
PMID:39291062
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11404745/
Abstract

Primary central nervous system lymphoma (PCNSL) is a rare, aggressive variant of extranodal non-Hodgkin's lymphoma. Although gadolinium-enhanced magnetic resonance imaging remains the initial imaging modality of choice, a whole-body F-18 fluorodeoxyglucose (FDG) positron emission tomography-computed tomography is imperative to exclude systemic lymphomatous involvement. Furthermore, the metabolic parameter, maximum standardized uptake value (SUV) of the lesion, tumor-to-normal cerebral tissue SUV ratio, and FDG uptake patterns help in differentiating intracranial lymphomas from High-grade Glioblastoma Multiforme (HGM) and infectious lesions, and hence, consolidating the diagnosis. In this pictorial essay, we present a series of PCNSL cases, representing the different imaging characteristics and metabolic uptake patterns.

摘要

原发性中枢神经系统淋巴瘤（PCNSL）是结外非霍奇金淋巴瘤的一种罕见且侵袭性的亚型。尽管钆增强磁共振成像仍是首选的初始成像方式，但全身F-18氟脱氧葡萄糖（FDG）正电子发射断层扫描-计算机断层扫描对于排除系统性淋巴瘤累及至关重要。此外，病变的代谢参数、最大标准化摄取值（SUV）、肿瘤与正常脑组织的SUV比值以及FDG摄取模式有助于将颅内淋巴瘤与高级别多形性胶质母细胞瘤（HGM）和感染性病变区分开来，从而巩固诊断。在这篇影像学论文中，我们展示了一系列PCNSL病例，呈现出不同的影像学特征和代谢摄取模式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f92/11404745/116a90459fb3/IJNM-39-191-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f92/11404745/1ebe810b57a3/IJNM-39-191-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f92/11404745/6d598febf9cf/IJNM-39-191-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f92/11404745/dc1ec0bda1a2/IJNM-39-191-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f92/11404745/1d5d84d786d9/IJNM-39-191-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f92/11404745/ab2badc11b0d/IJNM-39-191-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f92/11404745/484f8c2a4c84/IJNM-39-191-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f92/11404745/119d28b511f9/IJNM-39-191-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f92/11404745/116a90459fb3/IJNM-39-191-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f92/11404745/1ebe810b57a3/IJNM-39-191-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f92/11404745/6d598febf9cf/IJNM-39-191-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f92/11404745/dc1ec0bda1a2/IJNM-39-191-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f92/11404745/1d5d84d786d9/IJNM-39-191-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f92/11404745/ab2badc11b0d/IJNM-39-191-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f92/11404745/484f8c2a4c84/IJNM-39-191-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f92/11404745/119d28b511f9/IJNM-39-191-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f92/11404745/116a90459fb3/IJNM-39-191-g008.jpg

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本文引用的文献

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Different facets of intracranial central nervous system lymphoma and its imaging mimics.颅内中枢神经系统淋巴瘤的不同方面及其影像表现的模拟情况。
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