Prabhu Meghana, Nisamudeen Fahad, Vikas H
Department of Nuclear Medicine, Amrita Institute of Medical Sciences, Faridabad, Haryana, India.
Department of Nuclear Medicine, Institute of Liver and Biliary Sciences, New Delhi, India.
Indian J Nucl Med. 2024 May-Jun;39(3):185-190. doi: 10.4103/ijnm.ijnm_5_23. Epub 2024 Aug 17.
Role of FDG PET/CT in evaluation of biliary tract diseases remains relatively unexplored. PET/CT with FDG helps in evaluation of both infective / inflammatory as well as neoplastic diseases as increased glucose utilization is observed in both the conditions. In this article, we describe the spectrum of FDG PET/CT findings in various diseases affecting the biliary tract. Role of FDG PET/CT in neoplastic diseases involving the biliary duct has been described at the time of staging and response evaluation; in characterization of the intrahepatic mass (abscess v/s cholangiocarcinoma). In addition, we have discussed about the false positive FDG uptake along the biliary duct stent, which interfere with scan interpretation. Few of the benign conditions described are Langerhans cell histiocytosis and IgG4 related disease involving the biliary duct and adenomyomatosis and Xanthogranulomatous cholecystitis involving the gall bladder.
氟代脱氧葡萄糖正电子发射断层显像/计算机断层扫描(FDG PET/CT)在胆道疾病评估中的作用仍相对未被充分探索。含氟代脱氧葡萄糖的PET/CT有助于评估感染性/炎症性疾病以及肿瘤性疾病,因为在这两种情况下均观察到葡萄糖利用率增加。在本文中,我们描述了FDG PET/CT在影响胆道的各种疾病中的表现谱。FDG PET/CT在胆管肿瘤性疾病分期和疗效评估以及肝内肿块(脓肿与胆管癌)鉴别诊断中的作用已被阐述。此外,我们还讨论了沿胆管支架出现的FDG摄取假阳性情况,这会干扰扫描结果的解读。所描述的一些良性疾病包括累及胆管的朗格汉斯细胞组织细胞增多症和IgG4相关疾病,以及累及胆囊的腺肌增生症和黄色肉芽肿性胆囊炎。