Yuan Haichuan, Huang Min, Liu Tao, Song Wu, Luo Chengpeng
Department of Urology, Renhe Hospital, Shanghai, 200431, People Republic of China.
Preventive Health Care Section, Gaojing Town Community Health Service Center, Shanghai, 200435, People Republic of China.
Open Med (Wars). 2024 Sep 13;19(1):20241026. doi: 10.1515/med-2024-1026. eCollection 2024.
To investigate the effect of three-dimensional (3D) reconstruction-assisted cognitive fusion in targeted prostate biopsy.
There was no significant difference in the detection rate of prostate cancer (PCa) between targeted biopsy and systematic biopsy, and there was significant difference in the detection rate of clinically significant prostate cancer (csPCa) between targeted biopsy and systematic biopsy. In the low prostate total specific antigen (tPSA) group, there was no statistically significant difference in the detection rate of prostate cancer between the two biopsy modalities. However, compared with systematic puncture, targeted puncture had a higher detection rate for csPCa and a lower detection rate for clinically insignificant prostate cancer (ciPCa), and the difference was statistically significant. In the high tPSA group, there was no significant difference in the detection rate of PCa, csPCa, and ciPCa between the two biopsy types. Single needle positive rate of targeted puncture (29.77%) was significantly higher than that of systematic puncture (10.28%).
The detection rate of csPCa in 3D reconstruction-assisted cognitive fusion targeted prostate biopsy is better than that of 12-needle systematic biopsy, which markedly improved the positive rate of prostate biopsy.
探讨三维（3D）重建辅助认知融合在靶向前列腺穿刺活检中的作用。
靶向活检与系统活检在前列腺癌（PCa）检出率上无显著差异，而在临床显著前列腺癌（csPCa）检出率上存在显著差异。在前列腺总特异性抗原（tPSA）水平较低的组中，两种活检方式在前列腺癌检出率上无统计学显著差异。然而，与系统穿刺相比，靶向穿刺对csPCa的检出率更高，对临床意义不显著的前列腺癌（ciPCa）的检出率更低，且差异具有统计学意义。在tPSA水平较高的组中，两种活检类型在PCa、csPCa和ciPCa的检出率上无显著差异。靶向穿刺的单针阳性率（29.77%）显著高于系统穿刺（10.28%）。
三维重建辅助认知融合靶向前列腺活检中csPCa的检出率优于12针系统活检，显著提高了前列腺穿刺活检的阳性率。
