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Defying the odds: 30 years in AL amyloidosis research-recent barriers to clinical trial enrollment.

作者信息

Sanchorawala Vaishali, Barroso Bruna, Shelton Anthony, Goetz Elise, Mendelson Lisa, Joshi Tracy, Burke Natasha, Sloan J Mark, Staron Andrew

机构信息

Department of Medicine, Amyloidosis Center, Boston University Chobanian & Avedisian School of Medicine, Boston Medical Center, Boston, MA.

Department of Medicine, Cancer and Hematology Clinical Research Program, Boston Medical Center, Boston, MA.

出版信息

Blood Adv. 2024 Nov 26;8(22):5826-5828. doi: 10.1182/bloodadvances.2024014262.

DOI:10.1182/bloodadvances.2024014262
PMID:39293090
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11609355/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9382/11609355/ad8a01d5c76b/BLOODA_ADV-2024-014262-gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9382/11609355/ad8a01d5c76b/BLOODA_ADV-2024-014262-gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9382/11609355/ad8a01d5c76b/BLOODA_ADV-2024-014262-gr1.jpg

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本文引用的文献

1
Systemic Light Chain Amyloidosis.系统性轻链型淀粉样变性
N Engl J Med. 2024 Jun 27;390(24):2295-2307. doi: 10.1056/NEJMra2304088.
2
The clinical trials landscape in immunoglobulin light chain amyloidosis: a systematic review.免疫球蛋白轻链淀粉样变性的临床试验概况:一项系统综述。
Blood Adv. 2024 Jul 9;8(13):3464-3467. doi: 10.1182/bloodadvances.2024012737.
3
Do recruitment SWAT interventions have an impact on participant retention in randomised controlled trials? A systematic review.招募 SWAT 干预措施对随机对照试验中参与者的保留率有影响吗?一项系统评价。
Clin Trials. 2024 Apr;21(2):233-241. doi: 10.1177/17407745231206283. Epub 2023 Oct 25.
4
Guidelines for non-transplant chemotherapy for treatment of systemic AL amyloidosis: EHA-ISA working group.系统性AL淀粉样变性非移植化疗治疗指南:欧洲血液学协会-国际淀粉样变性协会工作组
Amyloid. 2023 Mar;30(1):3-17. doi: 10.1080/13506129.2022.2093635. Epub 2022 Jul 15.
5
Predictors of hematologic response and survival with stem cell transplantation in AL amyloidosis: A 25-year longitudinal study.干细胞移植治疗淀粉样变性的血液学反应和生存预测因素:25 年的纵向研究。
Am J Hematol. 2022 Sep;97(9):1189-1199. doi: 10.1002/ajh.26641. Epub 2022 Jul 5.
6
Increasing Racial and Ethnic Diversity in Cancer Clinical Trials: An American Society of Clinical Oncology and Association of Community Cancer Centers Joint Research Statement.提高癌症临床试验中的种族和民族多样性:美国临床肿瘤学会和社区癌症中心协会联合研究声明。
J Clin Oncol. 2022 Jul 1;40(19):2163-2171. doi: 10.1200/JCO.22.00754. Epub 2022 May 19.
7
Update on the Contemporary Treatment of Light Chain Amyloidosis Including Stem Cell Transplantation.关于轻链淀粉样变性的当代治疗方法,包括干细胞移植的最新进展。
Am J Med. 2022 Apr;135 Suppl 1:S30-S37. doi: 10.1016/j.amjmed.2022.01.011. Epub 2022 Jan 23.
8
Guidelines for high dose chemotherapy and stem cell transplantation for systemic AL amyloidosis: EHA-ISA working group guidelines.系统性淀粉样变高剂量化疗和干细胞移植治疗指南:EHA-ISA 工作组指南。
Amyloid. 2022 Mar;29(1):1-7. doi: 10.1080/13506129.2021.2002841. Epub 2021 Nov 16.
9
Marked progress in AL amyloidosis survival: a 40-year longitudinal natural history study.AL 淀粉样变性生存的显著进展:一项 40 年的纵向自然史研究。
Blood Cancer J. 2021 Aug 4;11(8):139. doi: 10.1038/s41408-021-00529-w.
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Race/ethnicity in systemic AL amyloidosis: perspectives on disease and outcome disparities.系统性 AL 淀粉样变性中的种族/民族:对疾病和结局差异的看法。
Blood Cancer J. 2020 Nov 10;10(11):118. doi: 10.1038/s41408-020-00385-0.