Brand Fiona, Bale Elizabeth, Tsiachristas Apostolos, Hawton Keith
Oxford Healthcare NHS Foundation Trust, Oxford, UK.
Centre for Suicide Research, University of Oxford, Oxford, UK.
BJPsych Open. 2024 Sep 19;10(5):e155. doi: 10.1192/bjo.2024.740.
Self-poisoning with paracetamol is the most frequently used overdose method in the UK. Psychosocial assessments were conducted by mental health clinicians with 127 consecutive individuals who presented with pure paracetamol overdoses to a large general hospital over 8 months, including asking about the source of the tablets and scoring the patients' acts on the Beck Suicide Intent scale (BSI). Patients were predominantly female (86%) and young (79% aged 12-24 years). Most had used paracetamol which was available in the home (77%). Those who purchased paracetamol for the act took double the number of tablets compared with those who used paracetamol available in the home (37 18), had higher suicidal intent (mean BSI: 11 7) and more often required treatment with -acetyl cysteine (71% 43%). These results highlight the need for safer home storage of paracetamol and consideration of reducing pack size limits on paracetamol that can be purchased.
对乙酰氨基酚自我中毒是英国最常用的过量服药方法。心理健康临床医生对连续127名在8个月内到一家大型综合医院就诊的纯对乙酰氨基酚过量服药患者进行了心理社会评估，包括询问药片来源并根据贝克自杀意念量表（BSI）对患者行为进行评分。患者主要为女性（86%）且年轻（79%年龄在12至24岁之间）。大多数人服用的是家中备有的对乙酰氨基酚（77%）。为过量服药而购买对乙酰氨基酚的人服用的药片数量是使用家中现有对乙酰氨基酚的人的两倍（37片对18片），有更高的自杀意念（平均BSI：11对7），且更常需要用N - 乙酰半胱氨酸治疗（71%对43%）。这些结果凸显了更安全地在家中储存对乙酰氨基酚以及考虑减少可购买的对乙酰氨基酚包装规格限制的必要性。
