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蛋白丢失性肠病与CD4 + T细胞免疫缺陷合并缩窄性心包炎

Protein-Losing Enteropathy and CD4+ T-Cell Immunodeficiency Complicated by Constrictive Pericarditis.

作者信息

Kim Yoo Jin, Gami Abhishek, Schumacher Sarah, Belanger Matthew, Umapathi Priya

机构信息

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

出版信息

JACC Case Rep. 2024 Aug 21;29(16):102463. doi: 10.1016/j.jaccas.2024.102463.

DOI:10.1016/j.jaccas.2024.102463
PMID:39295798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11405948/
Abstract

is a rare and often fatal cause of pericarditis. This paper presents a patient with heart failure with preserved ejection fraction, CD4+ T-cell deficiency, and constrictive pericarditis. This case highlights a rare association between heart failure and immunodeficiency, in addition to the multidisciplinary management of constrictive pericarditis.

摘要

是一种罕见且常致命的心包炎病因。本文介绍了一名射血分数保留的心力衰竭、CD4 + T细胞缺乏且患有缩窄性心包炎的患者。该病例除了强调缩窄性心包炎的多学科管理外，还突出了心力衰竭与免疫缺陷之间的罕见关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37eb/11405948/97288fe91b8f/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37eb/11405948/da1f87945e5a/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37eb/11405948/0148531096e1/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37eb/11405948/f1f7ac28f177/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37eb/11405948/7d03848c9b57/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37eb/11405948/1c083950d0c1/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37eb/11405948/97288fe91b8f/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37eb/11405948/da1f87945e5a/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37eb/11405948/0148531096e1/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37eb/11405948/f1f7ac28f177/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37eb/11405948/7d03848c9b57/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37eb/11405948/1c083950d0c1/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37eb/11405948/97288fe91b8f/gr5.jpg

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本文引用的文献

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Protein-Losing Enteropathy.蛋白丢失性肠病
N Engl J Med. 2023 Aug 24;389(8):733-748. doi: 10.1056/NEJMra2301594.
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pericarditis in a lymphoma patient: Case report and literature review.一名淋巴瘤患者的心包炎：病例报告及文献综述
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Idiopathic CD4 Lymphocytopenia: Current Insights.特发性CD4淋巴细胞减少症：当前见解
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Protein-Losing Enteropathy in Patients With Congenital Heart Disease.先天性心脏病患者的蛋白丢失性肠病。
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An unusual case of fatal pericarditis due to Listeria monocytogenes.李斯特菌性化脓性心包炎致死 1 例
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Idiopathic CD4+ T-cell lymphocytopenia is associated with impaired membrane expression of the chemokine receptor CXCR4.特发性 CD4+ T 细胞淋巴细胞减少症与趋化因子受体 CXCR4 的膜表达受损有关。
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Curr Opin Rheumatol. 2006 Jul;18(4):389-95. doi: 10.1097/01.bor.0000231908.57913.2f.
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Acquired combined immunodeficiency associated with protein losing enteropathy complicating Fontan operation.与蛋白丢失性肠病相关的获得性联合免疫缺陷，并发于Fontan手术。
Heart. 2003 Oct;89(10):1130-1. doi: 10.1136/heart.89.10.1130.
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Cellular immunodeficiency in protein-losing enteropathy. Predominant reduction of CD3+ and CD4+ lymphocytes.蛋白丢失性肠病中的细胞免疫缺陷。CD3⁺和CD4⁺淋巴细胞显著减少。
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