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制药4.0:深入探讨高层管理对加纳制药制造业成功实施精益4.0的承诺。

Pharma 4.0: A deep dive top management commitment to successful Lean 4.0 implementation in Ghanaian pharma manufacturing sector.

作者信息

Grace Tetteh Michelle, Gupta Sumit, Kumar Mukesh, Trollman Hana, Salonitis Konstantinos, Jagtap Sandeep

机构信息

Sustainable Manufacturing Systems Centre, Cranfield University, Cranfield, MK43 0AL, UK.

Department of Mechanical Engineering, A.S.E.T., Amity University, Uttar Pradesh, Noida, 201313, India.

出版信息

Heliyon. 2024 Aug 29;10(17):e36677. doi: 10.1016/j.heliyon.2024.e36677. eCollection 2024 Sep 15.

Abstract

The primary aim of this study is to assess the significance of top management commitment in the context of Lean 4.0 implementation within the pharmaceutical manufacturing industry in Ghana. The study seeks to understand and evaluate the overall effectiveness and achievements associated with adopting Lean 4.0. Employing a positivist mindset, the research utilizes an explanatory quantitative research design and a survey technique. Data collected from 181 employees of pharmaceutical companies in Ghana undergo analysis using SmartPLS (version 4) and IBM SPSS version 26. The study employs a combination of descriptive statistics to summarise data characteristics and inferential statistics to test various hypotheses related to Lean 4.0 adoption. The analysis reveals that the successful integration of lean methods and Industry 4.0 technologies requires meticulous management. Simultaneously, individual implementations of lean principles and Industry 4.0 technologies positively impact business performance. Surprisingly, the study does not observe a substantial positive influence of Lean 4.0 on corporate performance, suggesting that immediate improvements in efficiency or profitability may not result from the adoption of this framework. This research contributes to the field by highlighting the need for careful management in integrating lean methods and Industry 4.0 technologies. It also emphasizes the positive impacts of lean principles and Industry 4.0 technology on business performance. The unexpected finding regarding the lack of immediate improvements in corporate efficiency or profitability with Lean 4.0 adoption prompts considerations of initial implementation challenges or the organization's need for time to adapt to this integrated approach.

摘要

本研究的主要目的是评估在加纳制药行业实施精益4.0的背景下,高层管理承诺的重要性。该研究旨在了解和评估与采用精益4.0相关的整体有效性和成就。本研究采用实证主义思维方式,运用解释性定量研究设计和调查技术。从加纳制药公司的181名员工收集的数据使用SmartPLS(版本4)和IBM SPSS版本26进行分析。该研究采用描述性统计和推断性统计相结合的方法,以总结数据特征并检验与采用精益4.0相关的各种假设。分析表明,精益方法与工业4.0技术的成功整合需要精心管理。同时,精益原则和工业4.0技术的单独实施对企业绩效有积极影响。令人惊讶的是,该研究没有观察到精益4.0对公司绩效有实质性的积极影响,这表明采用这一框架可能不会立即带来效率或盈利能力的提升。本研究通过强调在整合精益方法和工业4.0技术时需要谨慎管理,为该领域做出了贡献。它还强调了精益原则和工业4.0技术对企业绩效的积极影响。关于采用精益4.0未能立即提高公司效率或盈利能力这一意外发现,促使人们考虑初始实施挑战或组织适应这种综合方法所需的时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c388/11408067/32d0d13c77d0/gr1.jpg

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