Xu Shan-Shan, Zhu Shi-Guo, Yuan Cheng-Xiang, Zeng Guo-Ling, Li Xiao-Tian, Liu Rong-Pei, Huang Shi-Shi, Zhang Xiong, Wang Jian-Yong
Department of Neurology, Institute of Geriatric Neurology, the Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China.
Front Hum Neurosci. 2024 Sep 4;18:1464152. doi: 10.3389/fnhum.2024.1464152. eCollection 2024.
Freezing of gait (FOG) is a disabling and heterogeneous symptom in patients with Parkinson's disease (PD). Among them, dopamine-induced FOG is rare and difficult to identify. The treatment of dopamine-induced FOG is complex.
We herein presented a case of PD patient who complicated with refractory FOG. It was identified as dopamine-induced FOG during levodopa challenge test. Her symptoms were alleviated after we reduced the total equivalent dosage of levodopa.
Our report emphasizes the importance of levodopa challenge test in identifying different types of FOG, which is very important for further adjusting treatment.
冻结步态(FOG)是帕金森病(PD)患者中一种致残且异质性的症状。其中,多巴胺诱导的FOG罕见且难以识别。多巴胺诱导的FOG的治疗很复杂。
我们在此报告一例合并难治性FOG的PD患者。在左旋多巴激发试验中被确定为多巴胺诱导的FOG。在我们降低左旋多巴的总等效剂量后,她的症状得到缓解。
我们的报告强调了左旋多巴激发试验在识别不同类型FOG中的重要性,这对进一步调整治疗非常重要。