Yılmaz Hamdi
Turk Psikiyatri Derg. 2024 Sep 19;36:56-61. doi: 10.5080/u27284.
COVID-19 may affect central nervous system. The symptoms related to the CNS may occur through the direct neuroinvasion of the virus, inflammation, autoimmunity, psychosocial stressors and treatment side effects. COVID-19 can increase the severity of existing mental illnesses and also trigger the onset of a new mental illness. In this case report, we present a 52-year-old male patient with no previous psychiatric history as well as no family history of mental illness. The patient's manic symptoms began while he was hospitalized due to severe COVID-19 pneumonia. The patient, who self-discharged himself from the hospital was brought to the emergency department involuntarily by his relatives 14 days later and was admitted to the psychiatry service. In this case report, possible etiological factors were discussed and the treatment course during the hospitalization and one year follow-up were presented. Our aim is to contribute to the literature by discussing possible etiological factors and management of mania that started during the treatment of COVID-19. COVID-19 can affect the central nervous system and be associated with psychiatric symptoms. Keywords: COVID-19, Mania, Bipolar Disorder, Central Nervous System.
新型冠状病毒肺炎(COVID-19)可能会影响中枢神经系统。与中枢神经系统相关的症状可能通过病毒的直接神经侵袭、炎症、自身免疫、心理社会应激源以及治疗副作用而出现。COVID-19会加重现有精神疾病的严重程度,还会引发新的精神疾病。在本病例报告中,我们介绍了一名52岁男性患者,他既往无精神病史,家族中也无精神疾病史。该患者因重症COVID-19肺炎住院期间出现躁狂症状。患者自行出院,14天后被亲属非自愿送至急诊科,并入住精神科。在本病例报告中,我们讨论了可能的病因,并介绍了住院期间及一年随访期间的治疗过程。我们的目的是通过讨论COVID-19治疗期间出现躁狂的可能病因及管理方法,为文献提供参考。COVID-19可影响中枢神经系统并伴有精神症状。关键词:COVID-19、躁狂、双相情感障碍、中枢神经系统