Decker S, Müller-Färber J, Decker B
Z Plast Chir. 1979 Sep;3(3):159-75.
Up to 5 days after an transplantation of autogenous cancellous bone in a defect of the ulna of dog which was stabilized by osteosynthesis no remarkable osteoblastic cell activity can be made out by light microscopy using the semithin sectioning technique. On the other hand, there is an obvious increase of osteogenic cells which normally only occur in small numbers in adult dog's cancellous bone of the iliac crest. Only after 7 days, numerous typical osteoblasts can be detected in association with transplanted cancellous chips, osteoblasts which seem to originate from the osteogenic cells by mitotic divisions. One week after the test's commencement, an extensive revascularisation of the transplant can be noticed as well. The osteoblastic cell activity and the forming of new bone are obviously dependent on a sufficient vascular supply in autogenous cancellous graft. The high osteogenic power of an autogenous cancellous graft is based on the ability of survival of the osteogenic cells, which proliferate and differentiate into osteoblasts in the course of one week, wherever its are close enough to functioning capillaries.
在用骨固定术稳定的犬尺骨缺损处自体松质骨移植后长达5天的时间里，使用半薄切片技术通过光学显微镜观察不到明显的成骨细胞活性。另一方面，成骨细胞明显增多，而成骨细胞在成年犬髂嵴的松质骨中通常数量很少。仅在7天后，在移植的松质骨碎片周围可检测到大量典型的成骨细胞，这些成骨细胞似乎是通过有丝分裂从成骨细胞分化而来的。在试验开始一周后，还可观察到移植骨有广泛的血管再生。成骨细胞活性和新骨形成明显依赖于自体松质骨移植中有足够的血管供应。自体松质骨移植的高成骨能力基于成骨细胞的存活能力，这些成骨细胞在一周内增殖并分化为成骨细胞，只要它们足够接近功能正常的毛细血管。
