Division of Pediatric Neurology, Department of Pediatrics, University of Michigan, C.S. Mott Children's Hospital, Ann Arbor, Michigan, USA.
Curr Opin Pediatr. 2024 Dec 1;36(6):630-643. doi: 10.1097/MOP.0000000000001399. Epub 2024 Sep 11.
Critically ill children are at risk of neurologic dysfunction and acquiring primary and secondary brain injury. Close monitoring of cerebral function is crucial to prevent, detect, and treat these complications.
A variety of neuromonitoring modalities are currently used in pediatric and neonatal ICUs. These include noninvasive modalities, such as electroencephalography, transcranial Doppler, and near-infrared spectroscopy, as well as invasive methods including intracranial pressure monitoring, brain tissue oxygen measurement, and cerebral microdialysis. Each modality offers unique insights into neurologic function, cerebral circulation, or metabolism to support individualized neurologic care based on a patient's own physiology. Utilization of these modalities in ICUs results in reduced neurologic injury and mortality and improved neurodevelopmental outcomes.
Monitoring of neurologic function can significantly improve care of critically ill children. Additional research is needed to establish normative values in pediatric patients and to standardize the use of these modalities.
危重症患儿存在神经功能障碍和原发性及继发性脑损伤的风险。密切监测脑功能对于预防、发现和治疗这些并发症至关重要。
目前在儿科和新生儿重症监护病房(NICU)中使用了多种神经监测方式。这些方式包括非侵入性方式,如脑电图、经颅多普勒和近红外光谱,以及侵入性方法,包括颅内压监测、脑组织氧测量和脑微透析。每种方式都提供了对神经功能、脑循环或代谢的独特见解,以根据患者自身的生理情况支持个体化的神经护理。在 ICU 中使用这些方式可降低神经损伤和死亡率,并改善神经发育结局。
监测神经功能可显著改善危重症患儿的护理。需要进一步研究以在儿科患者中建立正常参考值,并规范这些方式的使用。