黄曲霉毒素B1在人肝脏中的代谢 - Suppr | 超能文献

The metabolism of aflatoxin B1 by human liver.

作者信息

Moss E J, Neal G E

出版信息

Biochem Pharmacol. 1985 Sep 1;34(17):3193-7. doi: 10.1016/0006-2952(85)90170-4.

DOI:10.1016/0006-2952(85)90170-4

Abstract

摘要

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The metabolism of aflatoxin B1 by human liver.黄曲霉毒素B1在人肝脏中的代谢

Biochem Pharmacol. 1985 Sep 1;34(17):3193-7. doi: 10.1016/0006-2952(85)90170-4.

2

Metabolic basis of the species difference to aflatoxin B1 induced hepatotoxicity.物种对黄曲霉毒素B1诱导的肝毒性差异的代谢基础。

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3

The formation of 2,3-dihydroxy-2,3-dihydro-aflatoxin B1 by the metabolism of aflatoxin B1 by liver microsomes isolated from certain avian and mammalian species and the possible role of this metabolite in the acute toxicity of aflatoxin B1.从某些禽类和哺乳动物物种中分离出的肝微粒体对黄曲霉毒素B1进行代谢生成2,3 - 二羟基 - 2,3 - 二氢黄曲霉毒素B1，以及该代谢产物在黄曲霉毒素B1急性毒性中可能发挥的作用。

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4

Comparative study on the metabolism and activation of aflatoxin B1 in nuclet, microsomes and reconstituted P-450 system of rat liver.

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5

The formation of 2,3-dihydro-2,3-dihydroxy aflatoxin B1 by the metabolism of aflatoxin B1 in vitro by rat liver microsomes.黄曲霉毒素B1在大鼠肝脏微粒体体外代谢过程中形成2,3-二氢-2,3-二羟基黄曲霉毒素B1 。

FEBS Lett. 1979 May 15;101(2):382-6. doi: 10.1016/0014-5793(79)81049-2.

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Species susceptibility to aflatoxin B1 carcinogenesis: comparative kinetics of microsomal biotransformation.物种对黄曲霉毒素B1致癌作用的易感性：微粒体生物转化的比较动力学

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Aflatoxin M1: in vitro preparation and comparative in vitro metabolism versus aflatoxin B1 in the rat and mouse.

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Spontaneous reactions of aflatoxin B1 modified deoxyribonucleic acid in vitro.黄曲霉毒素B1修饰的脱氧核糖核酸在体外的自发反应。

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Induction of lysis in lysogenic bacteria by liver microsomal metabolites of aflatoxin B1.黄曲霉毒素B1的肝脏微粒体代谢产物对溶原性细菌的裂解诱导作用。

Indian J Exp Biol. 1980 Oct;18(10):1162-4.

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The effect of schistosomiasis on the activation of aflatoxin B1.血吸虫病对黄曲霉毒素B1激活的影响。

Res Commun Chem Pathol Pharmacol. 1986 Mar;51(3):421-4.

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Comparative metabolism of aflatoxin B in mouse, rat and human primary hepatocytes using HPLC-MS/MS.采用 HPLC-MS/MS 比较研究黄曲霉毒素 B 在小鼠、大鼠和人原代肝细胞中的代谢。

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2

A novel aldehyde reductase with activity towards a metabolite of aflatoxin B1 is expressed in rat liver during carcinogenesis and following the administration of an anti-oxidant.一种对黄曲霉毒素B1的代谢产物具有活性的新型醛还原酶在大鼠肝脏癌变过程中以及给予抗氧化剂后表达。

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Monitoring of aflatoxins and ochratoxin A in Czechoslovak human sera by immunoassay.

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