Farrands P A, O'Regan D, Taylor I
Br J Surg. 1985 Oct;72(10):835-7. doi: 10.1002/bjs.1800721020.
One hundred and fifty-two consecutive patients with symptoms suggestive of colorectal disease were offered occult blood testing before undergoing barium enema examination or colonoscopy; one hundred and thirty-nine successfully completed the test. Thirty-four had positive results of whom thirteen had a cancer and eight an adenomatous polyp (diagnostic yield for neoplasia of 59 per cent). No false negative results occurred, a sensitivity of 100 per cent, and only 21 false positives occurred, a specificity for malignancy of 84 per cent. Subjects attending outpatients should be offered occult blood testing; those with a positive test should undergo colonoscopy. The cost-benefit of such a scheme is emphasized.
152例有结肠直肠疾病症状的连续患者在接受钡灌肠检查或结肠镜检查前接受了潜血检测；139例成功完成检测。34例结果呈阳性，其中13例患有癌症，8例患有腺瘤性息肉（肿瘤诊断率为59%）。未出现假阴性结果，敏感性为100%，仅出现21例假阳性结果，恶性肿瘤特异性为84%。门诊患者应接受潜血检测；检测呈阳性者应接受结肠镜检查。强调了该方案的成本效益。
