氨甲环酸联合微针治疗黄褐斑的系统评价。
The Use of Tranexamic Acid and Microneedling in the Treatment of Melasma: A Systematic Review.
机构信息
Idowu D. Olugbade is from the Warren Alpert Medical School of Brown University, Providence, Rhode Island. Dr. Negbenebor is from the Department of Dermatology, University of Iowa, Iowa City.
出版信息
Cutis. 2024 Aug;114(2):E15-E23. doi: 10.12788/cutis.1080.
Melasma is a chronic pigmentary disorder that results in hyperpigmented patches in sun-exposed areas. Tranexamic acid (TXA) and microneedling are potential treatment options for individuals with melasma. The objective of our systematic review was to review 12 randomized controlled trials and clinical trials on the use and efficacy of TXA with microneedling for melasma. The combination of TXA and microneedling was found to be more effective at improving melasma lesions than either treatment alone; TXA alone was equally effective at reducing melasma lesions vs the standard treatment of hydroquinone.
黄褐斑是一种慢性色素沉着疾病，导致暴露在阳光下的区域出现色素沉着斑块。氨甲环酸 (TXA) 和微针是治疗黄褐斑患者的潜在选择。我们的系统评价旨在回顾 12 项关于 TXA 联合微针治疗黄褐斑的随机对照试验和临床试验，以评估其疗效。TXA 联合微针治疗黄褐斑的疗效优于单一治疗；与氢醌的标准治疗相比，TXA 单独治疗黄褐斑的疗效相当。
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