Chen Feifan, Jia Yifan, Xiao Ling, Yang Li, Yang Jinlin, Zeng Jianmei, Xu Limao, Xiao Xue
Department of Gastroenterology and Hepatology, West China Hospital of Sichuan University, Chengdu, China; Sichuan University-University of Oxford Huaxi Joint Centre for Gastrointestinal Cancer, West China Hospital of Sichuan University, Chengdu, China.
Department of Gastroenterology and Hepatology, West China Tianfu Hospital, Sichuan University, Chengdu, China.
Gastrointest Endosc. 2025 Feb;101(2):446-451. doi: 10.1016/j.gie.2024.09.020. Epub 2024 Sep 18.
Nonvariceal GI bleeding (GIB) is a common medical emergency. Endoscopic hemostasis is recommended, but some patients experienced recurrent bleeding after conventional endoscopic hemostasis. Originally, the purse-string suture (PSS) was used for lesion closure during EMR. Here, we evaluated the effectiveness of the endoscopic PSS in controlling refractory bleeding.
We retrospectively collected data from 3 hospitals of patients who underwent endoscopic PSS for refractory nonvariceal GIB. Clinical success was defined as no recurrent bleeding, and patients were discharged according to medical advice.
From October 2017 to May 2024, 36 patients who received PSS treatments were included. Of these 36 patients, 83.3% (30) achieved clinical success. In refractory upper GIB, the clinical success rate was 81.25% (26/32), and in lower GIB, the clinical success rate was 100% (4/4).
The endoscopic PSS is effective in treating refractory nonvariceal GIB.
非静脉曲张性消化道出血（GIB）是一种常见的医疗急症。推荐采用内镜止血，但部分患者在常规内镜止血后仍会出现复发性出血。最初，荷包缝合术（PSS）用于内镜黏膜切除术（EMR）期间的病变闭合。在此，我们评估了内镜下PSS控制难治性出血的有效性。
我们回顾性收集了3家医院接受内镜下PSS治疗难治性非静脉曲张性GIB患者的数据。临床成功定义为无复发性出血，患者根据医嘱出院。
2017年10月至2024年5月，纳入36例接受PSS治疗的患者。在这36例患者中，83.3%（30例）取得临床成功。在难治性上消化道出血中，临床成功率为81.25%（26/32），在下消化道出血中，临床成功率为100%（4/4）。
内镜下PSS治疗难治性非静脉曲张性GIB有效。
