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耳压作为 2 型糖尿病的辅助治疗:数据挖掘和荟萃分析。

Auricular pressure as an adjuvant treatment for type 2 diabetes: data mining and meta-analysis.

机构信息

School of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China.

Department of Endocrinology, The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, China.

出版信息

Front Endocrinol (Lausanne). 2024 Sep 5;15:1424304. doi: 10.3389/fendo.2024.1424304. eCollection 2024.

DOI:10.3389/fendo.2024.1424304
PMID:39301316
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11410687/
Abstract

OBJECTIVE

This study aimed to explore the clinical efficacy and acupoint combinations of auricular pressure for treating type 2 diabetes.

METHODS

Eight common databases were searched for publications related to auricular pressure in type 2 diabetes as of November 2023. A meta-analysis was performed to assess the efficacy and safety of auricular pressure therapy. Data mining was used to analyze the core acupoints for auricular pressure.

RESULTS

Meta-analysis demonstrated that compared with the conventional treatment group, the combined auricular pressure and conventional treatment group had significantly reduced fasting blood glucose (mean difference [MD]: -0.93; 95% confidence interval [CI]: -1.17 to -0.68; < 0.00001), 2-hour postprandial blood glucose (MD: -1.58; 95% CI: -2.04 to -1.12; < 0.00001), glycated hemoglobin A1c (MD: -0.83; 95% CI: -1.19 to -0.48; < 0.00001), total cholesterol (MD: -0.43; 95% CI: -0.72 to -0.14; = 0.004), triglycerides (MD: -0.33; 95% CI: -0.64 to -0.03; < 0.00001), systolic blood pressure (MD: -14.75; 95% CI: -24.46 to -5.05; = 0.003), diastolic blood pressure (MD: -10.32; 95% CI: -20.14 to -0.50; = 0.04), and body mass index (MD: -1.74; 95% CI: -2.61 to -0.87; < 0.0001), while adverse events were comparable (RR: 0.84; 95% CI: 0.43 to 1.66; = 0.61). Egger's test revealed no publication bias ( = 0.715). Data mining identified AH, TF, AT, CO, and CO as core acupoints for treating type 2 diabetes with auricular pressure.

CONCLUSION

Auricular pressure safely improves blood glucose and lipid levels, blood pressure, and body mass index in patients with type 2 diabetes. A regimen consisting of AH, TF, AT, CO, and CO is expected to serve as a complementary treatment for type 2 diabetes.

SYSTEMATIC REVIEW REGISTRATION

www.crd.york.ac.uk/prospero/display_record.php?RecordID=524887, identifier CRD42024524887.

摘要

目的

本研究旨在探讨耳压治疗 2 型糖尿病的临床疗效和穴位组合。

方法

截至 2023 年 11 月,检索了 8 个常用数据库中关于耳压治疗 2 型糖尿病的相关文献。采用荟萃分析评估耳压疗法的疗效和安全性。数据挖掘用于分析耳压的核心穴位。

结果

荟萃分析表明,与常规治疗组相比,耳压联合常规治疗组空腹血糖(均差 [MD]:-0.93;95%置信区间 [CI]:-1.17 至 -0.68; < 0.00001)、餐后 2 小时血糖(MD:-1.58;95% CI:-2.04 至 -1.12; < 0.00001)、糖化血红蛋白 A1c(MD:-0.83;95% CI:-1.19 至 -0.48; < 0.00001)、总胆固醇(MD:-0.43;95% CI:-0.72 至 -0.14; = 0.004)、三酰甘油(MD:-0.33;95% CI:-0.64 至 -0.03; < 0.00001)、收缩压(MD:-14.75;95% CI:-24.46 至 -5.05; = 0.003)、舒张压(MD:-10.32;95% CI:-20.14 至 -0.50; = 0.04)和体重指数(MD:-1.74;95% CI:-2.61 至 -0.87; < 0.0001)均显著改善,且不良反应相当(RR:0.84;95% CI:0.43 至 1.66; = 0.61)。Egger 检验未发现发表偏倚( = 0.715)。数据挖掘确定了 AH、TF、AT、CO 和 CO 是治疗 2 型糖尿病的核心穴位。

结论

耳压安全地改善了 2 型糖尿病患者的血糖和血脂水平、血压和体重指数。AH、TF、AT、CO 和 CO 组成的方案有望成为 2 型糖尿病的辅助治疗方法。

系统评价注册

www.crd.york.ac.uk/prospero/display_record.php?RecordID=524887,标识符 CRD42024524887。

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