Mujić Jahić Indira, Gojkov Vukelić Mirjana, Hadžić Sanja, Pašić Enes, Muharemović Arma, Salihefendić Lana, Konjhodžić Rijad
Department of Periodontology and Oral Medicine, Faculty of Dentistry with the Dental-Clinical Center, University of Sarajevo, Sarajevo, BIH.
Alea Genetic Center, Health Institute Alea Dr. Kandić, Sarajevo, BIH.
Cureus. 2024 Aug 19;16(8):e67252. doi: 10.7759/cureus.67252. eCollection 2024 Aug.
This comprehensive research aimed to thoroughly examine the effectiveness of a diode laser (445 nm) in combination with non-surgical treatment in patients with chronic periodontitis (CP) by evaluating a wide range of clinical and microbiological parameters.
Thirty-one subjects diagnosed with CP were included in this study. The total number of treated periodontal pockets was 862. The subjects were randomly assigned to group 1, which underwent scaling and root planing and laser therapy (SRP+L), and group 2, which underwent scaling and root planing (SRP) only. All respondents underwent a periodontal diagnostic protocol. The parameters plaque index (PI), gingival index (GI), bleeding on probing index (BOP), probing depth (PD), clinical attachment level (CAL), and tooth mobility (TM) were registered. Clinical periodontal measurements were performed at baseline and one and three months after therapy. Microbiological analysis was conducted on (Aa), (Pg), and (Tf) using real-time polymerase chain reaction (PCR). For microbiological analysis, samples were taken at baseline, immediately after therapy, and after three months. Laser irradiation was performed immediately after SRP.
All clinical parameters improved statistically from baseline to three months after therapy. For all examined clinical parameters, better results were achieved in group 1 than in group 2. This study showed a more significant reduction in Pg and Tf from baseline to three months in group 1 compared to group 2.
These results showed that the diode laser wavelength 445 nm was also usable in treating periodontal diseases as an additional method to SRP.
这项综合研究旨在通过评估一系列临床和微生物学参数,全面检验二极管激光(445纳米)联合非手术治疗对慢性牙周炎(CP)患者的有效性。
本研究纳入了31名被诊断为CP的受试者。治疗的牙周袋总数为862个。受试者被随机分为两组,第1组接受龈下刮治术、根面平整术和激光治疗(SRP+L),第2组仅接受龈下刮治术和根面平整术(SRP)。所有受试者均接受牙周诊断方案。记录菌斑指数(PI)、牙龈指数(GI)、探诊出血指数(BOP)、探诊深度(PD)、临床附着水平(CAL)和牙齿松动度(TM)等参数。在基线、治疗后1个月和3个月进行临床牙周测量。使用实时聚合酶链反应(PCR)对伴放线放线杆菌(Aa)、牙龈卟啉单胞菌(Pg)和具核梭杆菌(Tf)进行微生物分析。对于微生物分析,在基线、治疗后即刻和3个月后采集样本。在SRP后立即进行激光照射。
从基线到治疗后3个月,所有临床参数在统计学上均有改善。对于所有检查的临床参数,第1组的结果优于第2组。本研究表明,与第2组相比,第1组从基线到3个月时Pg和Tf的减少更为显著。
这些结果表明,445纳米的二极管激光波长作为SRP的辅助方法,也可用于治疗牙周疾病。