Vasin N Ia, Nadvornik P, Lesov N, Kadin A L, Shramka M
Zh Vopr Neirokhir Im N N Burdenko. 1979 Nov-Dec(6):23-8.
The work is based on the results of operations on the cerebellar dentate nuclei in 92 patients. In 42 of them, combined manipulations were carried out on the cerebellar dentate nuclei and the diencephalic structures (relay nuclei, median centre, pulvinar and subthalamus). Analysis of the results showed that stereotaxic destruction of the ventrooral parts of the cerebellar dentate nucleus is a very effective surgical manipulation in various forms of spastic dyskinesia. A natural decrease in the spastic component of the muscular hypertonia is the principal clinical effect of dentatotomy. Its effect on the rigid component of muscular hypertension is negligible. Combined manipulations on the cerebellar dentate nuclei and diencephalic structures are indicated in cases with combined spastic conditions and hyperkinesia which cannot be corrected by dentatotomy. The analysis of the results of combined interventions on the nuclear structures of the thalamus shows that pulvinarotomy is most effective, it reduces or corrects hyperkinesia in infantile cerebral paralysis and, in addition, causes diminution of the general hypertonia, of the upper extremities before all else. Proper rehabilitation treatment is the decisive factor in the final outcomes of stereotaxic intervention on the cerebellar motor systems and on those of the diencephalon in spastic forms of hyperkinesia.
这项工作基于对92例患者小脑齿状核的手术结果。其中42例患者对小脑齿状核和间脑结构(中继核、正中核、丘脑枕和下丘脑)进行了联合手术操作。结果分析表明,小脑齿状核腹侧口部的立体定向毁损术在各种形式的痉挛性运动障碍中是一种非常有效的手术操作。肌张力过高的痉挛成分自然降低是齿状核切开术的主要临床效果。其对肌张力过高的强直成分的影响可忽略不计。对于合并痉挛状态和运动亢进且无法通过齿状核切开术纠正的病例,需对小脑齿状核和间脑结构进行联合手术操作。对丘脑核结构联合干预结果的分析表明,丘脑枕切开术最为有效,它可减轻或纠正婴儿脑瘫中的运动亢进,此外,首先会使上肢的全身肌张力降低。在痉挛性运动亢进形式下,适当的康复治疗是对小脑运动系统和间脑运动系统进行立体定向干预最终结果的决定性因素。