• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

加强基础:评估子宫韧带完整性在子宫脱垂及其他方面的作用。

Fortifying the foundation: assessing the role of uterine ligament integrity in uterine prolapse and beyond.

机构信息

Department of Gynecology, Obstetrics and Reproduction Medicine, Saarland University, Kirrbergerstraße 100, Building 9, 66424, Homburg, Germany.

Clinic for Gynecology and Obstetrics, University Clinical Center of Serbia, 11000, Belgrade, Serbia.

出版信息

Arch Gynecol Obstet. 2024 Nov;310(5):2333-2343. doi: 10.1007/s00404-024-07732-7. Epub 2024 Sep 20.

DOI:10.1007/s00404-024-07732-7
PMID:39302411
Abstract

BACKGROUND

Pelvic floor stability is influenced by various biomechanical, anatomical, and physiological factors. Understanding these dynamics is crucial for improving the treatment of pelvic organ prolapse (POP) and related conditions.

OBJECTIVE

To analyze the key factors affecting pelvic floor integrity and explore both non-surgical and surgical interventions to enhance stability and treatment outcomes.

METHODS

This review draws from biomechanical research to assess the role of the uterosacral ligament in pelvic support, while also examining the potential of both traditional and emerging therapeutic approaches, including non-surgical interventions like vitamin C supplementation.

RESULTS

  • The uterosacral ligament demonstrates superior strength and stiffness, making it essential for structural support of pelvic organs. - Non-surgical interventions, such as vitamin C supplementation, show potential in improving ligament integrity and preventing pelvic floor disorders. - Emerging surgical techniques, including tendon-based procedures and injectable fibrous hydrogel composites, offer promising improvements in outcomes for patients with pelvic organ prolapse. - Additional factors such as muscle strength and neural deficiencies contribute to the complexity of pelvic floor biomechanics, indicating the need for multifaceted treatment approaches.

CONCLUSION

This analysis provides a comprehensive framework for understanding and managing pelvic floor stability by integrating biomechanical, physiological, and anatomical insights. The findings highlight the potential for personalized treatment strategies to improve patient outcomes in pelvic floor disorders.

摘要

背景

骨盆底稳定性受多种生物力学、解剖学和生理学因素的影响。了解这些动态变化对于改善盆腔器官脱垂(POP)及相关病症的治疗至关重要。

目的

分析影响骨盆底完整性的关键因素,并探讨增强稳定性和治疗效果的非手术和手术干预措施。

方法

本综述借鉴生物力学研究,评估了子宫骶骨韧带在骨盆支撑中的作用,同时研究了传统和新兴治疗方法的潜力,包括非手术干预措施,如维生素 C 补充。

结果

  • 子宫骶骨韧带具有优越的强度和刚性,对于盆腔器官的结构支撑至关重要。- 非手术干预措施,如维生素 C 补充,显示出改善韧带完整性和预防骨盆底疾病的潜力。- 新兴的手术技术,包括基于肌腱的手术和可注射纤维性水凝胶复合材料,为患有盆腔器官脱垂的患者提供了改善治疗效果的前景。- 其他因素,如肌肉力量和神经缺陷,增加了骨盆底生物力学的复杂性,表明需要采用多方面的治疗方法。

结论

本分析通过整合生物力学、生理学和解剖学的见解,提供了一个全面的框架来理解和管理骨盆底稳定性。研究结果强调了个性化治疗策略在改善盆腔底疾病患者治疗效果方面的潜力。

相似文献

1
Fortifying the foundation: assessing the role of uterine ligament integrity in uterine prolapse and beyond.加强基础:评估子宫韧带完整性在子宫脱垂及其他方面的作用。
Arch Gynecol Obstet. 2024 Nov;310(5):2333-2343. doi: 10.1007/s00404-024-07732-7. Epub 2024 Sep 20.
2
From molecular to macro: the key role of the apical ligaments in uterovaginal support.从分子到宏观:顶韧带在阴道子宫支持中的关键作用。
Am J Obstet Gynecol. 2020 May;222(5):427-436. doi: 10.1016/j.ajog.2019.10.006. Epub 2019 Oct 19.
3
What's new in the functional anatomy of pelvic organ prolapse?盆腔器官脱垂功能解剖学的新进展有哪些?
Curr Opin Obstet Gynecol. 2016 Oct;28(5):420-9. doi: 10.1097/GCO.0000000000000312.
4
Platelet rich plasma as a minimally invasive approach to uterine prolapse.富血小板血浆作为子宫脱垂的一种微创治疗方法。
Med Hypotheses. 2017 Jul;104:97-100. doi: 10.1016/j.mehy.2017.05.018. Epub 2017 May 25.
5
[Comparison outcomes of three surgical procedures in treatment of severe pelvic organ prolapse and analysis of risk factors for genital prolapse recurrence].[三种手术治疗重度盆腔器官脱垂的比较结果及生殖器脱垂复发危险因素分析]
Zhonghua Fu Chan Ke Za Zhi. 2011 Feb;46(2):94-100.
6
Laparoscopic inguinal ligament suspension with uterine preservation for pelvic organ prolapse: A retrospective cohort study.腹腔镜下保留子宫的腹股沟韧带悬吊术治疗盆腔器官脱垂:一项回顾性队列研究。
Int J Surg. 2018 Jun;54(Pt A):28-34. doi: 10.1016/j.ijsu.2018.04.020. Epub 2018 Apr 16.
7
Laparoscopic Uterosacral Ligament Hysteropexy vs Total Vaginal Hysterectomy with Uterosacral Ligament Suspension for Anterior and Apical Prolapse: Surgical Outcome and Patient Satisfaction.腹腔镜子宫骶骨韧带固定术与经阴道全子宫切除术联合子宫骶骨韧带悬吊术治疗前位和前顶脱垂:手术结果和患者满意度。
J Minim Invasive Gynecol. 2020 Jan;27(1):88-93. doi: 10.1016/j.jmig.2019.02.012. Epub 2019 Feb 22.
8
Using the novel pelvic organ prolapse histologic quantification system to identify phenotypes in uterosacral ligaments in women with pelvic organ prolapse.采用新型盆腔器官脱垂组织学量化系统鉴定盆腔器官脱垂患者阴道骶骨韧带的表型。
Am J Obstet Gynecol. 2021 Jan;224(1):67.e1-67.e18. doi: 10.1016/j.ajog.2020.10.040. Epub 2020 Oct 30.
9
Effect of Uterosacral Ligament Suspension vs Sacrospinous Ligament Fixation With or Without Perioperative Behavioral Therapy for Pelvic Organ Vaginal Prolapse on Surgical Outcomes and Prolapse Symptoms at 5 Years in the OPTIMAL Randomized Clinical Trial.Uterosacral 韧带悬吊术与骶棘韧带固定术联合或不联合围手术期行为疗法治疗盆腔器官阴道脱垂 5 年的手术结果和脱垂症状的影响:OPTIMAL 随机临床试验。
JAMA. 2018 Apr 17;319(15):1554-1565. doi: 10.1001/jama.2018.2827.
10
[Long-term effectiveness of transvaginal high uterosacral ligament suspension].经阴道高位骶子宫韧带悬吊术的长期疗效
Zhonghua Fu Chan Ke Za Zhi. 2017 Jun 25;52(6):363-368. doi: 10.3760/cma.j.issn.0529-567X.2017.06.002.

引用本文的文献

1
Impact of Milk Consumption and Dietary Patterns on Pelvic Organ Prolapse: A Mendelian Randomization Study.牛奶摄入量和饮食模式对盆腔器官脱垂的影响:一项孟德尔随机化研究。
Int J Womens Health. 2025 Jun 19;17:1837-1847. doi: 10.2147/IJWH.S519596. eCollection 2025.
2
To rest or not to rest after sacral colpopexy? Dispelling an old custom in the ERAS time.骶骨阴道固定术后是否需要休息?消除ERAS时代的旧习俗。
Arch Gynecol Obstet. 2025 Mar;311(3):863-870. doi: 10.1007/s00404-024-07904-5. Epub 2025 Jan 20.

本文引用的文献

1
Potential molecular targets for intervention in pelvic organ prolapse.盆腔器官脱垂干预的潜在分子靶点。
Front Med (Lausanne). 2023 Sep 5;10:1158907. doi: 10.3389/fmed.2023.1158907. eCollection 2023.
2
Analysis of the anatomical and biomechanical characteristics of the pelvic floor in cystocele.分析膀胱膨出患者盆底的解剖和生物力学特征。
Acta Obstet Gynecol Scand. 2023 Dec;102(12):1661-1673. doi: 10.1111/aogs.14657. Epub 2023 Aug 26.
3
Supramolecular Fibrous Hydrogel Augmentation of Uterosacral Ligament Suspension for Treatment of Pelvic Organ Prolapse.
纤维状超分子水凝胶增强子宫骶骨悬带在治疗盆腔器官脱垂中的应用。
Adv Healthc Mater. 2023 Sep;12(22):e2300086. doi: 10.1002/adhm.202300086. Epub 2023 May 31.
4
From thigh to pelvis: female genital prolapse repair with an autologous semitendinosus tendon transplant : Data of the German multicenter trial.从大腿到骨盆:采用自体半腱肌腱移植修复女性生殖器脱垂:德国多中心试验数据
Int Urogynecol J. 2023 Oct;34(10):2373-2380. doi: 10.1007/s00192-023-05512-6. Epub 2023 May 2.
5
Phylogeography of (Meliaceae) Complex in China Inferred from Cytonuclear Markers.中国(楝科)复合体的系统地理学研究——基于核质标记。
Genes (Basel). 2022 Dec 31;14(1):116. doi: 10.3390/genes14010116.
6
Creation of the biomechanical finite element model of female pelvic floor supporting structure based on thin-sectional high-resolution anatomical images.基于薄层高分辨率解剖图像构建女性盆底支持结构的生物力学有限元模型。
J Biomech. 2023 Jan;146:111399. doi: 10.1016/j.jbiomech.2022.111399. Epub 2022 Nov 25.
7
AbsorbaTack vs. ProTack vs. sutures: a biomechanical analysis of cervical fixation methods for laparoscopic apical fixations in the porcine model.AbsorbaTack 与 ProTack 缝线对比:猪模型腹腔镜顶切固定中颈椎固定方法的生物力学分析。
Arch Gynecol Obstet. 2023 Mar;307(3):863-871. doi: 10.1007/s00404-022-06827-3. Epub 2022 Nov 20.
8
[Two-dimensional equivalent mechanical modeling and finite element analysis of normal female pelvic floor system].[正常女性盆底系统的二维等效力学建模与有限元分析]
Zhonghua Yi Xue Za Zhi. 2022 Jul 26;102(28):2189-2195. doi: 10.3760/cma.j.cn112137-20211108-02478.
9
Decreased expression of transcription factor Homeobox A11 and its potential target genes in bladder cancer.转录因子 Homeobox A11 及其潜在靶基因在膀胱癌中的表达降低。
Pathol Res Pract. 2022 May;233:153847. doi: 10.1016/j.prp.2022.153847. Epub 2022 Mar 21.
10
Uterosacral Ligament Suspension Sec Shull by Vaginal Natural Transluminal Endoscopic Surgery (vNOTES).经阴道自然腔道内镜手术(vNOTES)行子宫骶骨固定术(Sec Shull)。
J Obstet Gynaecol Can. 2022 Jun;44(6):703. doi: 10.1016/j.jogc.2022.02.126. Epub 2022 Mar 8.