State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, PR China.
State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, PR China.
Spectrochim Acta A Mol Biomol Spectrosc. 2025 Jan 15;325:125132. doi: 10.1016/j.saa.2024.125132. Epub 2024 Sep 14.
Sulfur dioxide (SO) derivatives are typically employed as antioxidants in food and pharmaceutical processing. However, excessive sulfite intake could trigger serious health problems. Hence, it is urgent to establish a rapid and effective system for monitoring SO. This study adopted a one-step hydrothermal method to synthesize dual-emitting nitrogen-doped carbon quantum dots (CECDs) and developed a ratiometric sensor for sulfite using CECDs-Cr (VI) composites. The emission intensity ratio (I/I) of the CECDs-Cr (VI) composites increased considerably with the addition of HSO. A method based on the ratiometric sensor was established for SO derivatives with advanced efficiency and excellent linearity over a broad concentration range of 0-500 μM (R = 0.9946). Four medicine-food homology materials (MFHMs) fumigated with sulfur have been accurately detected using this approach. Furthermore, a portable test tube was prepared to achieve rapid and semi-quantitative detection of SO residues and applied to real samples. This work presents an effective approach to develop a rapid on-site detection platform for sulfite residues in food and pharmaceuticals.
二氧化硫（SO）衍生物通常被用作食品和药物加工中的抗氧化剂。然而，过量的亚硫酸盐摄入可能会引发严重的健康问题。因此，建立一个快速有效的 SO 监测系统迫在眉睫。本研究采用一步水热法合成了双发射氮掺杂碳量子点（CECDs），并开发了一种基于 CECDs-Cr（VI）复合材料的亚硫酸盐比率传感器。随着 HSO 的加入，CECDs-Cr（VI）复合材料的发射强度比（I/I）显著增加。该比率传感器建立的方法具有先进的效率，在 0-500 μM （R = 0.9946）的宽浓度范围内具有优异的线性。该方法可以准确检测四种用硫磺熏蒸的药食同源材料（MFHMs）。此外，还制备了一个便携式试管，实现了对 SO 残留的快速半定量检测，并应用于实际样品。本工作为开发食品和药物中 SO 残留的快速现场检测平台提供了一种有效的方法。
