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作为肥胖症与神经疾病之间联系的类淋巴系统。

The glymphatic system as a nexus between obesity and neurological diseases.

作者信息

Chen Bandy, Lenck Stephanie, Thomas Jean-Leon, Schneeberger Marc

机构信息

Laboratory of Neurovascular Control of Homeostasis, Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT, USA.

Department of Neuroradiology, Pitié-Salpêtrière Hospital, Sorbonne University, Paris, France.

出版信息

Nat Rev Endocrinol. 2025 Jan;21(1):1-2. doi: 10.1038/s41574-024-01042-3.

Abstract

Exploring the glymphatic system across neurological and metabolic diseases might help us to better define the link between obesity and neurological disorders. Recent studies have identified metabolic dysfunction as a risk factor for cognitive decline and neurological disorders through disruption of the glymphatic system.

摘要

探索神经和代谢疾病中的类淋巴系统可能有助于我们更好地界定肥胖与神经障碍之间的联系。最近的研究已将代谢功能障碍确定为认知能力下降和神经障碍的一个风险因素,其途径是破坏类淋巴系统。

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