Rausa Vanessa C, Babl Franz E, Davies Katie, Takagi Michael, Davis Gavin A, McKinlay Audrey, Charles Bianca, Hearps Stephen J C, Anderson Nicholas, Clarke Cathriona, Barnett Peter, Dunne Kevin, Anderson Vicki
Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Australia.
Department of Paediatrics, The University of Melbourne, Melbourne, Australia.
Neuropsychol Rehabil. 2024 Sep 21:1-24. doi: 10.1080/09602011.2024.2402564.
This study examined the feasibility of "Concussion Essentials" (CE), an individualized, multimodal intervention for persisting post-concussion symptoms (pPCS). Thirteen 6-18 year-olds with pPCS at 1-month post-concussion, as determined by the Post Concussion Symptom Inventory - Parent Report (PCSI-P), completed education, physiotherapy, and psychology modules, for up to 8-weeks or until pPCS resolved. Intervention participants were matched to a longitudinal observational cohort who received usual care (n = 13). The study enrolled 70% of participants symptomatic on screening and the dropout rate was <30% between baseline and post-programme assessments (4-weeks to 3-months post-injury). Symptoms improved for 100% of CE participants, with the number of symptomatic items on the PCSI-P reducing from 4-weeks, Median (IQR) = 14.0 (8.0-19.0) to 3-months, Median (IQR) = 1.0 (0.0-5.0). Comparatively, symptoms improved for approximately half of matched usual care participants. CE participants (n = 8) and their parents (n = 11) completed acceptability questionnaires. Most parents (91%) agreed CE was acceptable for children with concussion. All participants agreed CE was appropriate for concussion, while approximately 88% agreed they enjoyed the intervention and would recommend CE to others. Findings suggest CE is a feasible and acceptable treatment for paediatric pPCS. Further investigation within a larger scale randomized clinical trial is warranted.
本研究探讨了“脑震荡要点”（CE）这一个性化多模式干预措施对持续性脑震荡后症状（pPCS）的可行性。根据脑震荡后症状量表家长报告版（PCSI-P）确定，13名在脑震荡后1个月出现pPCS的6至18岁儿童完成了教育、物理治疗和心理模块，为期长达8周或直至pPCS症状消失。干预参与者与接受常规护理的纵向观察队列（n = 13）进行匹配。该研究纳入了70%筛查时有症状的参与者，基线评估与项目后评估（受伤后4周-3个月）之间的脱落率<30%。100%的CE参与者症状得到改善，PCSI-P上有症状项目的数量从4周时的中位数（四分位间距）= 14.0（8.0 - 19.0）降至3个月时的中位数（四分位间距）= 1.0（0.0 - 5.0）。相比之下，匹配的常规护理参与者中约一半症状得到改善。CE参与者（n = 8）及其父母（n = 11）完成了可接受性问卷。大多数父母（91%）认为CE对脑震荡儿童是可接受的。所有参与者都认为CE适用于脑震荡，约88%的人表示喜欢该干预措施并会向他人推荐CE。研究结果表明，CE是治疗儿童pPCS的一种可行且可接受的方法。有必要在更大规模的随机临床试验中进行进一步研究。
