与碳酸锂相关的苔藓样口炎

Lichenoid stomatitis associated with lithium carbonate.

作者信息

Hogan D J, Murphy F, Burgess W R, Epstein J D, Lane P R

出版信息

J Am Acad Dermatol. 1985 Aug;13(2 Pt 1):243-6. doi: 10.1016/s0190-9622(85)70166-1.

Abstract

Lichenoid stomatitis has been reported in the use of a number of drugs. This is a case report of lichenoid stomatitis associated with lithium carbonate. The association between lichenoid stomatitis and lithium carbonate was confirmed by rechallenge in this patient. A number of cutaneous reactions have been reported as adverse effects of lithium therapy. Lichenoid reactions are characterized by an infiltrate of T cells. Lithium has been reported to alter T cell function in vitro.

摘要

已有报道多种药物使用时会出现苔藓样口炎。本文报告一例与碳酸锂相关的苔藓样口炎病例。该患者再次使用碳酸锂后，证实了苔藓样口炎与碳酸锂之间的关联。锂治疗的不良反应已有多种皮肤反应的报道。苔藓样反应的特征是T细胞浸润。据报道，锂在体外可改变T细胞功能。