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阴茎癌的全球负担:一种罕见疾病的健康差异综述

Global Burden of Penile Cancer: A Review of Health Disparities for a Rare Disease.

作者信息

Ogbuji Vanessa, Gomez D 'Andre Marquez, Paster Irasema Concepcion, Irizarry Von Marie Torres, McCormick Kyle, Dennis Leslie K, Recio-Boiles Alejandro, Chipollini Juan

机构信息

Department of Urology, University of Arizona College of Medicine, Tucson, AZ.

Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ.

出版信息

Urology. 2024 Dec;194:280-288. doi: 10.1016/j.urology.2024.09.029. Epub 2024 Sep 19.

DOI:10.1016/j.urology.2024.09.029
PMID:39306301
Abstract

We performed a narrative review evaluating the influence of race and socioeconomic status for penile cancer patients based on region. We found higher incidence in underdeveloped nations. Globally, HPV-associated tumors are more prevalent, particularly in areas with high HPV and HIV infection. Socioeconomic determinants exacerbated these disparities. Similarly, in the United States, disparities were notable among racial and ethnic groups, with black men having worse survival. Understanding sociodemographic differences may help mitigate disparities by improving access to care with targeted interventions including education on risk factors and HPV vaccination to reduce penile cancer burden in vulnerable parts of the world.

摘要

我们进行了一项叙述性综述,评估了地区因素对阴茎癌患者种族和社会经济地位的影响。我们发现,欠发达国家的发病率更高。在全球范围内,与人乳头瘤病毒(HPV)相关的肿瘤更为普遍,尤其是在HPV和艾滋病毒感染率高的地区。社会经济因素加剧了这些差异。同样,在美国,不同种族和族裔群体之间的差异也很显著,黑人男性的生存率更低。了解社会人口学差异可能有助于通过改善医疗服务可及性来减少差异,采取有针对性的干预措施,包括开展危险因素教育和HPV疫苗接种,以减轻世界上易受影响地区的阴茎癌负担。

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