Department of Neurology, BG-Hospital Bergmannstrost, 06112 Halle (Saale), Germany
Department of Neurology, BG-Hospital Bergmannstrost, 06112 Halle (Saale), Germany.
BMJ Case Rep. 2024 Sep 20;17(9):e260498. doi: 10.1136/bcr-2024-260498.
Intravascular large B-cell lymphoma (IVLBCL) is a rare type of non-Hodgkin's lymphoma. Common neurological symptoms are cognitive impairment and dementia. Only a few cases have been published reporting intracranial haemorrhage due to IVLBCL. We present a case of a female patient in her late 60s who presented with an atypical intracerebral haemorrhage as the first major complication of an IVLBCL. The patient's condition declined rapidly. She died several weeks later due to haemorrhagic shock. The definitive diagnosis was achieved postmortem. Due to aggressive disease progression, the diagnosis of IVLBCL is still challenging and can therefore lead to incorrect or delayed treatment, especially in cases of unusual manifestations like lobar intracranial haemorrhage.
血管内大 B 细胞淋巴瘤（IVLBCL）是一种罕见的非霍奇金淋巴瘤。常见的神经症状为认知障碍和痴呆。仅有少数病例报道因 IVLBCL 导致颅内出血。我们报告了一例 60 多岁的女性患者，她以非典型性颅内出血为 IVLBCL 的首发主要并发症。患者病情迅速恶化。数周后因失血性休克死亡。最终的诊断是在死后做出的。由于疾病进展迅速，IVLBCL 的诊断仍然具有挑战性，因此可能导致治疗不正确或延迟，特别是在像脑叶颅内出血这样不常见的表现的情况下。
