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主动脉球囊阻断复苏术(REBOA)在产后出血处理中的应用:一项综述性研究。

Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) as a strategy for postpartum haemorrhage management: A narrative review.

机构信息

Department of Intensive Care, Hôpital Universitaire de Bruxelles (HUB), Brussels, Belgium.

Department of Obstetrics and Gynecology, CHU Brugmann UVC, Brussels, Belgium.

出版信息

Int J Obstet Anesth. 2024 Nov;60:104260. doi: 10.1016/j.ijoa.2024.104260. Epub 2024 Aug 30.

DOI:10.1016/j.ijoa.2024.104260
PMID:39306573
Abstract

Postpartum hemorrhage (PPH) remains one of the leading causes of maternal mortality worldwide, with a significant impact on global health. Optimal management of PPH involves distinct steps executed simultaneously by a multidisciplinary approach, with anesthesiologists playing a key role in hemodynamic control and patient resuscitation. In this context, an aortic blood flow interruption through an internal balloon should be considered a rescue option among the various opportunities, to treat or prevent abdominal hemorrhages. Given this perspective, there is increasing interest in the role of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA), originally used in trauma and military medicine, which has emerged as a novel strategy for managing PPH. Indeed, this technique has shown promise in managing severe cases of PPH, especially where traditional measures are insufficient. It also offers potential as a prophylactic measure in pregnancies with high risk for PPH, such as in the case of placenta accrete spectrum. This review aims to examine the efficacy, safety, and potential applications of REBOA in PPH management and prevention. At the same time, challenges such as the need for skilled operators, potential complications, costs, and the consideration of fetal safety were also discussed. REBOA presents as a promising tool against PPH, with efficacy in reducing blood loss, preserving fertility, and potentially decreasing maternal mortality and improving outcomes. However, its implementation requires careful consideration, training, and further research to establish clear guidelines for its use in obstetric care.

摘要

产后出血 (PPH) 仍然是全球孕产妇死亡的主要原因之一,对全球健康有重大影响。PPH 的最佳管理涉及通过多学科方法同时执行的不同步骤,麻醉师在血流动力学控制和患者复苏方面发挥着关键作用。在这种情况下,通过内部气囊中断主动脉血流应被视为各种治疗机会之一,用于治疗或预防腹部出血。鉴于这种观点,人们对复苏性血管内主动脉球囊阻断术 (REBOA) 的作用越来越感兴趣,REBOA 最初用于创伤和军事医学,现已成为治疗 PPH 的一种新策略。事实上,这种技术在治疗严重的 PPH 病例方面显示出了希望,尤其是在传统措施不足的情况下。它还为 PPH 风险高的妊娠提供了作为预防措施的潜力,例如胎盘附着谱的情况。本综述旨在探讨 REBOA 在 PPH 管理和预防中的疗效、安全性和潜在应用。同时,还讨论了需要熟练操作人员、潜在并发症、成本以及对胎儿安全性的考虑等挑战。REBOA 是一种有前途的对抗 PPH 的工具,具有减少失血、保持生育能力以及降低孕产妇死亡率和改善结局的潜力。然而,其实施需要仔细考虑、培训和进一步研究,以建立其在产科护理中使用的明确指南。

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