Takorabet L, Carmès S, Dorfmann A, Dumontier C
Service d'orthopédie, CHU de Pointe à Pitre, 97139 Les Abymes, Guadeloupe.
Centre de la main, clinique Les Eaux Claires, ZAC Moudong Sud, 97122 Baie-Mahault, Guadeloupe.
Ann Chir Plast Esthet. 2025 Mar;70(2):96-103. doi: 10.1016/j.anplas.2024.08.011. Epub 2024 Sep 21.
There is no consensus on the utility of postoperative antibiotherapy in hand infections after surgical management. The aim of this study was to evaluate if the absence of postoperative antibiotic therapy was detrimental after surgical treatment.
We included 287 patients operated on for a hand infection between January 2018 and October 2023. Preoperative or postoperative antibiotic prescription was collected for every patient. Patients cured for their infection with a single surgery were classified as "simple evolution", while patients requiring repetitive surgery or who had at least one complication directly linked to the initial infection (extension of infection or necrosis) were considered "complicated".
From a total of 287 patients, we included 188 paronychia, 40 phlegmons, 47 abscesses and 12 superinfected wounds. The revision surgery rate was 9.4%, and the complication rate was 27.2%. One hundred and seventeen (40.8%) patients received preoperative antibiotic therapy from emergency physicians or general practitioners, among whom a complication rate of 31.6% was observed. The causal link did not reach the significance threshold for the whole group of patients (P=0.079). However, preoperative antibiotic use in phlegmon patients was directly correlated with the occurrence of at least one complication (P=0.032). In all, 82.9% of patients did not require postoperative antibiotic therapy, 95% of whom had an uncomplicated course.
Preoperative probabilistic antibiotic therapy is an independent risk factor for complications, particularly if given at a collected stage. Antibiotics should not be routinely prescribed postoperatively in a correct debridement is performed. We recommend that antibiotics be used only in very specific cases (osteitis, arthritis, necrosis and/or high-risk patients).
对于手术治疗手部感染后术后抗生素治疗的效用尚无共识。本研究的目的是评估手术治疗后不使用术后抗生素治疗是否有害。
我们纳入了2018年1月至2023年10月间因手部感染接受手术的287例患者。收集了每位患者术前或术后的抗生素处方。仅通过一次手术治愈感染的患者被归类为“病情简单进展”,而需要重复手术或至少有一项与初始感染直接相关的并发症(感染扩展或坏死)的患者被视为“复杂情况”。
在总共287例患者中,包括188例甲沟炎、40例脓性蜂窝织炎、47例脓肿和12例继发感染伤口。翻修手术率为9.4%,并发症发生率为27.2%。117例(40.8%)患者从急诊科医生或全科医生处接受了术前抗生素治疗,其中观察到并发症发生率为31.6%。对于整个患者群体,因果关系未达到显著阈值(P=0.079)。然而,脓性蜂窝织炎患者术前使用抗生素与至少发生一项并发症直接相关(P=0.032)。总体而言,82.9%的患者不需要术后抗生素治疗,其中95%的患者病情未出现复杂情况。
术前概率性抗生素治疗是并发症的独立危险因素,尤其是在收集阶段给予时。如果进行了正确的清创术,术后不应常规开具抗生素。我们建议仅在非常特殊的情况下使用抗生素(骨髓炎、关节炎、坏死和/或高危患者)。