Okamura K, Nakakuki M, Yamada K, Furukawa K, Koga S, Nakagawa K, Igarashi A
Jpn J Antibiot. 1985 May;38(5):1208-12.
A total of 15 cases of obstetrical and gynecological infections was treated with cefminox (CMNX, MT-141), a new cephamycin antibiotic, with following results. The subjects consisted of 3 cases of salpingitis, 2 cases of parametritis, 5 cases of endometritis, and 1 case each of puerperal fever, inflammation of the pelvic dead space, Bartholin's pyocele, vulvar abscess and suppurative mastitis. In 2 cases of endometritis, pelveoperitonitis and adnexitis were complicated, respectively. As a rule, CMNX was administered intravenously at a dosage of 1 g each twice a day by drip infusion route. The clinical results were rated as excellent in 8 cases, good in 6 cases and poor in 1 case, with an efficacy rate of 93.3%. No subjective or objective side effects were seen nor any abnormal laboratory test results were found.
应用新型头孢霉素类抗生素头孢米诺(CMNX,MT - 141)治疗妇产科感染15例,结果如下。患者包括输卵管炎3例、宫旁组织炎2例、子宫内膜炎5例,产褥热、盆腔死腔炎、巴氏腺脓肿、外阴脓肿及化脓性乳腺炎各1例。2例子宫内膜炎分别合并盆腔腹膜炎及附件炎。通常,头孢米诺通过静脉滴注给药,剂量为每日2次,每次1g。临床结果:8例为优,6例为良,1例为差,有效率为93.3%。未观察到主观或客观的副作用,实验室检查结果也未发现异常。