Cui Man, Wang Juan, Deng Miao, Meng Hailan, Fan Yanshuai, Ku Chaoyue, Wang Ruizhe, Wu Binbin, Dai Man, Ping Zhiguang
College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
Wei Sheng Yan Jiu. 2024 Sep;53(5):694-700. doi: 10.19813/j.cnki.weishengyanjiu.2024.05.002.
To explore the relationship between hypertensive comorbidity patterns and social participation and depressive symptoms in middle-aged and elderly hypertensive patients.
Using the data from the 2015, 2018 and 2020 of the China Health and Retirement Longitudinal Study, 2786 middle and elderly adults aged 45 and above with hypertension were included. Data analysis was performed in Stata 17.0 statistical software, using frequency and percentage to describe baseline characteristics. The generalized estimation equation(GEE) was used to to analyze the data, and GEE was constructed with the depressive symptoms of middle and elderly people as the dependent variable. The unifactorial and multifactorial analysis of the effects of hypertensive comorbidity patterns and social participation on depressive symptoms, and the influence of the interaction between hypertensive comorbidity patterns and social participation on depressive symptoms were analyzed.
Among the baseline characteristics of 2786 middle and older adults with hypertension, 2319(83.24%) had hypertensive comorbidity and 1558(55.92%) had social participant. The result of unifactorial GEE analysis of depressive symptoms in middle and older adults showed that the risk of depressive symptoms was higher in hypertensive comorbidity than in hypertension without comorbidity(OR=2.31, 95%CI 1.97-2.71, P<0.01), and lower in middle and older adults with social participation than in those without social participation(OR=0.71, 95%CI 0.64-0.78, P<0.01). The result of multifactorial GEE analysis of depressive symptoms in middle and older adults showed that the risk of depressive symptoms was higher in hypertensive comorbidity than in hypertension without comorbidity(OR=2.06, 95%CI 1.75-2.41, P<0.01), and lower in middle and older adults with social participation than in those without social participation(OR=0.78, 95%CI 0.70-0.87, P<0.01). Analysis of the interaction of hypertensive comorbidity and social participation on depressive symptoms in middle and older adults showed that middle and older adults with hypertensive comorbidity and no social participation had a 2.20 times higher risk of depressive symptoms than those with hypertension without comorbidity and no social participation(OR=2.20, 95%CI 1.78-2.72, P<0.01).
Comorbidity is severe in the hypertensive population, and social participation in the hypertensive comorbidity population may reduce the risk of developing depressive symptoms.
探讨中老年高血压患者的高血压合并症模式与社会参与及抑郁症状之间的关系。
利用中国健康与养老追踪调查2015年、2018年和2020年的数据，纳入2786名年龄在45岁及以上的患有高血压的中老年成年人。在Stata 17.0统计软件中进行数据分析，用频数和百分比描述基线特征。采用广义估计方程（GEE）进行数据分析，以中老年人群的抑郁症状作为因变量构建GEE。分析高血压合并症模式和社会参与对抑郁症状影响的单因素和多因素分析，以及高血压合并症模式与社会参与之间的交互作用对抑郁症状的影响。
在2786名患有高血压的中老年成年人的基线特征中，2319人（83.24%）患有高血压合并症，1558人（55.92%）有社会参与。中老年成年人抑郁症状的单因素GEE分析结果显示，高血压合并症患者出现抑郁症状的风险高于无合并症的高血压患者（OR=2.31，95%CI 1.97-2.71，P<0.01），有社会参与的中老年成年人出现抑郁症状的风险低于无社会参与的中老年成年人（OR=0.71，95%CI 0.64-0.78，P<0.01）。中老年成年人抑郁症状的多因素GEE分析结果显示，高血压合并症患者出现抑郁症状的风险高于无合并症的高血压患者（OR=2.06，95%CI 1.75-2.41，P<0.01），有社会参与的中老年成年人出现抑郁症状的风险低于无社会参与的中老年成年人（OR=0.78，95%CI 0.70-0.87，P<0.01）。中老年成年人高血压合并症与社会参与对抑郁症状的交互作用分析显示，患有高血压合并症且无社会参与的中老年成年人出现抑郁症状的风险比无合并症且无社会参与的高血压患者高2.20倍（OR=2.20，95%CI 1.78-2.72，P<0.01）。
高血压人群中合并症严重，高血压合并症人群的社会参与可能会降低出现抑郁症状的风险。
