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[视网膜血管阻塞:向缺氧区域直接供氧的可能性]

[Retinal vascular occlusion: possibilities of a direct oxygen supply to the hypoxic areas].

作者信息

Pournaras C J, Illic J, Gilodi N

出版信息

Klin Monbl Augenheilkd. 1985 Jun;186(6):485-7. doi: 10.1055/s-2008-1050965.

Abstract

Treatment of a retinal vascular occlusion consists in restoration of normal oxygenation to the affected area. An experimentally induced increase in arterial CO2 provokes an increase in preretinal CO2 in a hypoxic retinal area which has developed after venous obstruction, but it is ineffective in anoxic areas of an arterial occlusion. However, clinical application of this treatment offers no benefit for the patient. Hyperoxia caused by respiration of a gas mixture of 5% CO2 and 95% O2 is also ineffective. On the other hand, the results of recent studies in which blood is replaced with fluorocarbon solutions are promising. Finally, it is pointed out that in cases of venous occlusion laser coagulation leads to reoxygenation of the inner hypoxic retina.

摘要

视网膜血管阻塞的治疗在于恢复受影响区域的正常氧合。实验诱导动脉血二氧化碳增加会使静脉阻塞后形成的缺氧视网膜区域的视网膜前二氧化碳增加,但在动脉阻塞的缺氧区域无效。然而,这种治疗方法的临床应用对患者并无益处。吸入5%二氧化碳和95%氧气的混合气体所引起的高氧状态同样无效。另一方面,近期用氟碳溶液替代血液的研究结果很有前景。最后指出,在静脉阻塞的情况下,激光凝固可使内层缺氧视网膜重新获得氧合。

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