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酷似眼眶蜂窝织炎的鼻腔自然杀伤/ T细胞淋巴瘤:诊断难题。

Nasal natural killer/T-cell lymphoma mimicking orbital cellulitis: A diagnostic dilemma.

作者信息

Bhari Anju, Agrawal Sahil, Pushker Neelam, Das Prasenjit

机构信息

Senior Resident (Oculoplasty, Tumor & Pediatric Ophthalmology Services), Dr Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India.

Senior Research Officer (Oculoplasty, Tumor & Pediatric Ophthalmology Services), Dr Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India.

出版信息

Med J Armed Forces India. 2024 Sep-Oct;80(5):590-594. doi: 10.1016/j.mjafi.2022.09.012. Epub 2022 Nov 28.

Abstract

Nasal natural killer/T-cell lymphoma (NK/TCL) is a rare form of malignant non-Hodgkin lymphoma (NHL) with a far more rare involvement of orbit. The orbital involvement has a highly variable clinical presentation. Here, we report one such case of a 40-year-old male patient who presented with swelling in the right upper and lower eyelids with the diminution of vision for 12 days. He had a history of blocked nose for two months. Clinical examination and CT scan of the orbit and paranasal sinuses suggested a diagnosis of right orbital cellulitis with pansinusitis. A combination of intravenous antibiotics was started, and functional endoscopic sinus surgery was done. Histopathology was a suggestive of nasal NK/TCLl NHL. After proper staging, the patient was given chemotherapy and radiotherapy. There was a complete resolution of mass with no recurrence over a follow-up of 10 months.

摘要

鼻型自然杀伤细胞/T细胞淋巴瘤(NK/TCL)是一种罕见的恶性非霍奇金淋巴瘤(NHL),累及眼眶的情况更为罕见。眼眶受累的临床表现高度多变。在此,我们报告一例40岁男性患者,其右上睑和下睑肿胀伴视力减退12天。他有两个月的鼻塞病史。眼眶和鼻窦的临床检查及CT扫描提示诊断为右眼眶蜂窝织炎伴全鼻窦炎。开始联合静脉使用抗生素,并进行了功能性鼻内镜鼻窦手术。组织病理学提示为鼻型NK/TCL非霍奇金淋巴瘤。经过适当分期后,患者接受了化疗和放疗。肿块完全消退,在10个月的随访中无复发。

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本文引用的文献

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A TNM Staging System for Nasal NK/T-Cell Lymphoma.鼻型NK/T细胞淋巴瘤的TNM分期系统
PLoS One. 2015 Jun 22;10(6):e0130984. doi: 10.1371/journal.pone.0130984. eCollection 2015.
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Extranodal NK/T-cell lymphoma, nasal type: report of 15 cases.结外 NK/T 细胞淋巴瘤,鼻型:15 例报告。
Eur Ann Otorhinolaryngol Head Neck Dis. 2012 Jun;129(3):141-7. doi: 10.1016/j.anorl.2011.08.004. Epub 2012 Feb 7.

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